Executive Director, Global Medical Lead - HEME

General Summary

The Executive Director, Global Medical Lead (GML), HEME is a critical leadership role in Global Medical, responsible for the global medical strategy and implementation and tracking of global activities for a designated disease area(s).

Key Duties And Responsibilities

• Medical Strategy
  Develop, implement, execute, and communicate the Integrated Medical Plans, including but not limited to medical strategy, global tactical plan, publication, congress and post-approval evidence generation plan, in collaboration with Clinical Development, HEOR, RWE, Medical Writing, and other internal stakeholders across Vertex.

• Align medical strategy with organizational objectives by integrating individual and disease area team goals with Vertex and DST priorities, and the goals of cross-functional partners.

• Expertly distill insights and actionable outcomes that inform strategy and drive the greatest impact for Medical Affairs.

• Establish and track medical KPIs that demonstrate impact on business and patient outcomes.

• Apply structured problem-solving and root cause analysis to identify solutions and make decisions that maximize medical and business impact.

• Able to identify what is important and impactful to medical and the wider business, prioritize competing demands and communicate to key stakeholders.

• Develop the global disease area budget, manage funds allocation, and associated tracking to ensure alignment with Medical Affairs priorities and efficient resource allocation.

• Scientific Excellence
  Serve as product and disease area expert and primary contact point for all global disease area related issues with the external community and internally at Vertex.

• Able to lead development of peer-reviewed publications, congress presentations and evidence generation to shape clinical practice.

• Closely follow medical developments within disease area and disseminate new information to transform clinical trends and emerging data into new plans.

• Develop global scientific communications and materials including materials for global-led symposia, advisory boards, and training.

• Accountable for medical review of assigned brand-related content and global medical content aligned with Vertex SOPs.

• External Partnerships
  Represent Vertex at scientific and medical forums, including medical education forums, scientific societies, patient advocacy groups, and congresses.

• Engage and cultivate relationships with leading global key thought leaders (TL) to gain greater understanding of the disease area and insights into unmet patient needs.

• Medical Communication
  Tailor communication to stakeholder needs, building trust and understanding across diverse audiences.

• Deliver external presentations (advisory board meetings, symposia, other medical education meetings) to enhance the medical knowledge of pipeline and marketed products, as required and in accordance with relevant regulations and procedures.

• Support disease area training across the company as required.

• Regional Medical and Cross-Functional Collaboration
  Accountable for go-to-market model and medical partnership in commercialization with global cross-functional colleagues.

• In absence of regional teams, country go-to-market model remains the responsibility of the GML.

• Support regional Medical Affairs and Medical Excellence teams from launch through lifecycle via timely delivery of fit-for-purpose training and core materials.

• Responsible for driving alignment on medical content/messaging within the organization to ensure maximal functional and regional input.

• Medical Affairs leader on key global cross-functional product and development strategic focused teams, including DST and relevant sub-teams.

• Proactively communicate and represent medical needs to DST.

• Chair the Global Medical Area Team (GMAT) for the disease area and accountable for deliverables.

• Commercial & Enterprise Support
  Provide strategic Medical Affairs leadership on relevant commercial teams including Launch Team and Global Brand Teams.

• Represent Medical Affairs in label discussions.

• Support Access, Patient Advocacy, Policy, and Corporate Communications teams with medical/scientific expertise and materials review.

• Evidence Generation and Access
  Lead strategy, development, and execution of lifecycle management in partnership with HEOR, including Integrated Evidence Generation Plan.

• May act as medical monitor for studies falling under Medical Affairs scope.

• Lead oversight and management of ISS programs and scientific/medical review of protocols.

• As applicable, lead Managed Access Committee and/or act as Medical Monitor for Managed Access Programs Team.

• Team / People Management
  Provide strong leadership to disease area medical team.

• Accountable for recruitment, development, management, and coaching of the global medical team.

• Leverage team capabilities to ensure execution of medical plans.

• Identify and address skill gaps and future capability needs.

• Ensure goal-setting, performance cycles, and individual development plans.

• Navigate ambiguity and coach teams through change.

• Compliance and Pharmacovigilance
  Ensure compliance with global and regional guidelines, Vertex Code of Conduct, SOPs, GCP, and ICH.

• Ensure appropriate adverse event identification and reporting.

• Contribute to external communication when significant safety issues arise.

Education And Experience

• MD, PhD, PharmD, or other advanced life sciences degree required.

• Typically requires 15 years of experience and 7 years of supervisory/management experience.

• 6+ years of leadership experience in Medical Affairs and/or Clinical Development.

• 2+ years of industry experience in disease area.

Pay Range

$328,000 - $492,000