Executive Director, Clinical Pharmacology/Pharmacometrics
Recursion · Opportunity, NE · 3 wk ago
RemoteRemoteAnalyst$288k–$346k/yrFull-time
We need to output HTML fragment with sections: headings for sections like About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule. Only include sections with real content. We must not repeat job title as heading. Remove boilerplate, navigation, legal, EEO, etc. Also remove duplicated lines, application instructions.
We need to parse the job posting and extract relevant content.
Let's identify sections:
- About the role / Impact: "Your work will change lives. Including your own. The Impact You'll Make You will join an innovative and passionate clinical development team dedicated to improving the lives of patients suffering from devastating diseases. You will lead the innovative clinical pharmacology and pharmacometrics strategy and execution for a portfolio of rare disease and oncology clinical programs."
That's about the role.
- Responsibilities: The bullet list after "In This Role, You Will". Let's extract each sentence:
"Develop the clinical pharmacology and pharmacometric strategies to accelerate and support the overall product development plan."
"You’ll be the Clinical Pharmacology lead for various programs in clinical development, the representative for regulatory interactions, and propose innovative strategies to get therapies to patients faster."
"Solve drug development questions/problems by performing and/or overseeing modeling and simulation with various tools to expedite decision making."
"Design clinical studies. You’ll provide (clinical) pharmacology input on all clinical study designs, from Phase 1-3 and dedicated Phase 1 clinical pharmacology studies."
"Author review relevant clinical pharmacology sections for regulatory documents, including Investigator's Brochures (IB), INDs, NDAs, and other regulatory submissions."
"Act as the clinical pharmacology expert during interactions with health authorities."
"Interface with cross-functional teams. You’ll work closely with clinical study teams, translational teams (DMPK, Translational Modeling and Toxicology), preclinical teams and due diligence teams to ensure clinical pharmacology-related considerations are addressed."
That's responsibilities.
- The Team You’ll Join: description of team. Could be a section "Team" or maybe "About the Team". Could be under "About the role"? But we have a heading for "Team". We'll include a section maybe "Team". The heading could be "Team". But the allowed headings list includes: About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule. Not "Team". However we can still include a heading if we think it's appropriate? The instruction: "use
.
Now Pay: The posting says:
"Working Location & Compensation: This is a remote position based in the United States with required periodic travel. Qualifications At Recursion, we believe that every employee should be compensated fairly. Based on the skills, experience, and qualifications needed for this role, the estimated annual base salary range is: New York City, Boston, & San Francisco Bay Area(s): $287,980–$346,060 Salt Lake City & all other U.S. locations: $261,800–$314,600 In addition to base salary, this role is eligible for an annual bonus, equity compensation, and a comprehensive benefits package."
Thus Pay section should include salary ranges. We'll put that as a paragraph.
Benefits: mention annual bonus, equity compensation, comprehensive benefits package.
Schedule: remote position based in US with required periodic
for sections like About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule. Only include sections with real content. We must not repeat job title as heading. Remove boilerplate, navigation, legal, EEO, etc. Also remove duplicated lines, application instructions.
We need to parse the job posting and extract relevant content.
Let's identify sections:
- About the role / Impact: "Your work will change lives. Including your own. The Impact You'll Make You will join an innovative and passionate clinical development team dedicated to improving the lives of patients suffering from devastating diseases. You will lead the innovative clinical pharmacology and pharmacometrics strategy and execution for a portfolio of rare disease and oncology clinical programs."
That's about the role.
- Responsibilities: The bullet list after "In This Role, You Will". Let's extract each sentence:
"Develop the clinical pharmacology and pharmacometric strategies to accelerate and support the overall product development plan."
"You’ll be the Clinical Pharmacology lead for various programs in clinical development, the representative for regulatory interactions, and propose innovative strategies to get therapies to patients faster."
"Solve drug development questions/problems by performing and/or overseeing modeling and simulation with various tools to expedite decision making."
"Design clinical studies. You’ll provide (clinical) pharmacology input on all clinical study designs, from Phase 1-3 and dedicated Phase 1 clinical pharmacology studies."
"Author review relevant clinical pharmacology sections for regulatory documents, including Investigator's Brochures (IB), INDs, NDAs, and other regulatory submissions."
"Act as the clinical pharmacology expert during interactions with health authorities."
"Interface with cross-functional teams. You’ll work closely with clinical study teams, translational teams (DMPK, Translational Modeling and Toxicology), preclinical teams and due diligence teams to ensure clinical pharmacology-related considerations are addressed."
That's responsibilities.
- The Team You’ll Join: description of team. Could be a section "Team" or maybe "About the Team". Could be under "About the role"? But we have a heading for "Team". We'll include a section maybe "Team". The heading could be "Team". But the allowed headings list includes: About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule. Not "Team". However we can still include a heading if we think it's appropriate? The instruction: "use for section headings (e.g. About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule)." It says e.g., meaning those are examples, not exclusive? It says use for section headings (e.g. About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule). Likely they expect we use those headings when applicable. But we can also use other headings? The examples suggest those are typical sections; we could still use others if needed, but better to stick to those. The "Team" info could go under "About the role" or maybe "Qualifications"? Not exactly. Could be part of "About the role". We'll incorporate team description into About the role section.
- The Experience You’ll Need: This is qualifications/requirements. We'll put under "Requirements" or "Qualifications". The list includes education, experience, skills. We'll separate maybe "Requirements" for experience and "Qualifications" for education? But we can combine. The instruction: prefer few substantive sections over many thin ones. So we can have "Requirements" covering education, experience, skills. Or we could have "Qualifications" for education and "Skills" for technical skills. Let's see content:
Education: Ph.D. in Pharmaceutical Sciences, Pharmacokinetics or related discipline, M.D with a Clinical Pharmacology expertise, or a Pharm D. with a Clinical Pharmacology fellowship.
Experience: 10+ years of experience in biotech/pharmaceutical drug development.
Demonstrated success leading all clinical pharmacology related aspects of drug development.
Ability to work closely with internal and external stakeholders to manage PK, PK-PD, and PK-safety analyses, including non-compartmental analysis, population PK modeling, and PK-PD modeling and simulations to support dose selection, exposure-response and exposure-safety analyses through various phases of drug development.
Proficiency with WinNonlin, Monolix, NONMEM, R or other modeling software.
Effective skills directed toward driving collaboration, achieving results, influencing, and resolving conflicts across internal and external stakeholders
Demonstrated experience responding to regulatory agency questions, preparing clinical pharmacology aspects of regulatory submissions and attending regulatory meetings.
Highly motivated, decisive, and results-oriented individual who is proactive, resourceful, and efficient with the flexibility and creativity to excel in and contribute to a rapidly growing drug discovery and development company
Experience in oncology is preferred, but not an absolute requirement.
Thus we can put under "Requirements" (or "Qualifications").
- Working Location & Compensation: This includes remote position based in US with periodic travel, and salary ranges. That's Pay and maybe Schedule? The location and travel could be under "Schedule"? Not exactly. There's a "Pay" section for salary. Also "Benefits": mention annual bonus, equity compensation, comprehensive benefits package.
Thus we need sections: Pay, Benefits, maybe Schedule (if travel considered schedule). The posting says: "Working Location & Compensation: This is a remote position based in the United States with required periodic travel." That's location and travel; could be under "Schedule"? Not exactly schedule but maybe we can include under "Schedule" as "Remote position with periodic travel". However the instruction: never create Pay/Schedule/Benefits sections unless the posting actually states them. It does state compensation (salary range) and benefits (bonus, equity, benefits). So we can include Pay and Benefits. For Schedule, we have location and travel but not explicit schedule like full-time, hours. Might be considered schedule? The phrase "remote position based in the United States with required periodic travel" could be considered work arrangement, maybe under "Schedule". But we have to decide if we should include Schedule section. The instruction: prefer a few substantive sections over many thin ones. If we include Schedule with just that line, it's thin. Might be better to incorporate location/travel into About the role or maybe a separate "Work Location" but not in allowed headings. Could incorporate into Pay section? Not ideal. Perhaps we can include a "Schedule" section with that line. It's substantive enough? It's a sentence. Might be okay.
But we need to avoid filler like "not specified". This is specified.
Thus sections: About the role, Responsibilities, Requirements (or Qualifications), Pay, Benefits, Schedule.
We need to decide between Requirements and Qualifications. The posting includes both education and experience; we can put under "Requirements". Or we could have "Qualifications" for education and "Skills" for technical skills. But we have many skill items; better to combine.
Thus we will output:
About the role
for section headings (e.g. About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule). Likely they expect we use those headings when applicable. But we can also use other headings? The examples suggest those are typical sections; we could still use others if needed, but better to stick to those. The "Team" info could go under "About the role" or maybe "Qualifications"? Not exactly. Could be part of "About the role". We'll incorporate team description into About the role section.
- The Experience You’ll Need: This is qualifications/requirements. We'll put under "Requirements" or "Qualifications". The list includes education, experience, skills. We'll separate maybe "Requirements" for experience and "Qualifications" for education? But we can combine. The instruction: prefer few substantive sections over many thin ones. So we can have "Requirements" covering education, experience, skills. Or we could have "Qualifications" for education and "Skills" for technical skills. Let's see content:
Education: Ph.D. in Pharmaceutical Sciences, Pharmacokinetics or related discipline, M.D with a Clinical Pharmacology expertise, or a Pharm D. with a Clinical Pharmacology fellowship.
Experience: 10+ years of experience in biotech/pharmaceutical drug development.
Demonstrated success leading all clinical pharmacology related aspects of drug development.
Ability to work closely with internal and external stakeholders to manage PK, PK-PD, and PK-safety analyses, including non-compartmental analysis, population PK modeling, and PK-PD modeling and simulations to support dose selection, exposure-response and exposure-safety analyses through various phases of drug development.
Proficiency with WinNonlin, Monolix, NONMEM, R or other modeling software.
Effective skills directed toward driving collaboration, achieving results, influencing, and resolving conflicts across internal and external stakeholders
Demonstrated experience responding to regulatory agency questions, preparing clinical pharmacology aspects of regulatory submissions and attending regulatory meetings.
Highly motivated, decisive, and results-oriented individual who is proactive, resourceful, and efficient with the flexibility and creativity to excel in and contribute to a rapidly growing drug discovery and development company
Experience in oncology is preferred, but not an absolute requirement.
Thus we can put under "Requirements" (or "Qualifications").
- Working Location & Compensation: This includes remote position based in US with periodic travel, and salary ranges. That's Pay and maybe Schedule? The location and travel could be under "Schedule"? Not exactly. There's a "Pay" section for salary. Also "Benefits": mention annual bonus, equity compensation, comprehensive benefits package.
Thus we need sections: Pay, Benefits, maybe Schedule (if travel considered schedule). The posting says: "Working Location & Compensation: This is a remote position based in the United States with required periodic travel." That's location and travel; could be under "Schedule"? Not exactly schedule but maybe we can include under "Schedule" as "Remote position with periodic travel". However the instruction: never create Pay/Schedule/Benefits sections unless the posting actually states them. It does state compensation (salary range) and benefits (bonus, equity, benefits). So we can include Pay and Benefits. For Schedule, we have location and travel but not explicit schedule like full-time, hours. Might be considered schedule? The phrase "remote position based in the United States with required periodic travel" could be considered work arrangement, maybe under "Schedule". But we have to decide if we should include Schedule section. The instruction: prefer a few substantive sections over many thin ones. If we include Schedule with just that line, it's thin. Might be better to incorporate location/travel into About the role or maybe a separate "Work Location" but not in allowed headings. Could incorporate into Pay section? Not ideal. Perhaps we can include a "Schedule" section with that line. It's substantive enough? It's a sentence. Might be okay.
But we need to avoid filler like "not specified". This is specified.
Thus sections: About the role, Responsibilities, Requirements (or Qualifications), Pay, Benefits, Schedule.
We need to decide between Requirements and Qualifications. The posting includes both education and experience; we can put under "Requirements". Or we could have "Qualifications" for education and "Skills" for technical skills. But we have many skill items; better to combine.
Thus we will output:
About the role
... (combined impact and team description)
Responsibilities
- ... each responsibility
Requirements
- ... each requirement
Pay
... salary ranges
Benefits
... annual bonus, equity compensation, comprehensive benefits package.
Schedule
Remote position based in the United States with required periodic travel.
We must ensure we preserve all substantive information, not invent or summarize away detail. We must not omit any important details. Let's extract exact sentences. About the role: Combine first paragraph and team description. Original: "Your work will change lives. Including your own. The Impact You'll Make You will join an innovative and passionate clinical development team dedicated to improving the lives of patients suffering from devastating diseases. You will lead the innovative clinical pharmacology and pharmacometrics strategy and execution for a portfolio of rare disease and oncology clinical programs." Then later: "The Team You’ll Join You will join the Pharmacometrics team within Recursion comprising clinical pharmacology, pharmacometrics, and translational modeling. The Pharmacometrics group sits within Recursion’s Clinical Development organization. Team members get to sit on both Discovery and Development projects and work in a seamless end-to-end environment at Recursion. The team collaborates closely with clinical development functions (clinical science, clinical operations, regulatory affairs, biostatistics, etc.), as well as discovery functions (DMPK, Biology, Chemistry and Translational Biomarkers)." We should keep that as prose. Thus About the role paragraph: combine those. We must not repeat job title. Now Responsibilities: list each bullet. Let's list them exactly as in text: - Develop the clinical pharmacology and pharmacometric strategies to accelerate and support the overall product development plan. - You’ll be the Clinical Pharmacology lead for various programs in clinical development, the representative for regulatory interactions, and propose innovative strategies to get therapies to patients faster. - Solve drug development questions/problems by performing and/or overseeing modeling and simulation with various tools to expedite decision making. - Design clinical studies. You’ll provide (clinical) pharmacology input on all clinical study designs, from Phase 1-3 and dedicated Phase 1 clinical pharmacology studies. - Author review relevant clinical pharmacology sections for regulatory documents, including Investigator's Brochures (IB), INDs, NDAs, and other regulatory submissions. - Act as the clinical pharmacology expert during interactions with health authorities. - Interface with cross-functional teams. You’ll work closely with clinical study teams, translational teams (DMPK, Translational Modeling and Toxicology), preclinical teams and due diligence teams to ensure clinical pharmacology-related considerations are addressed. Check for any missing: The original also had "You’ll be the Clinical Pharmacology lead for various programs in clinical development, the representative for regulatory interactions, and propose innovative strategies to get therapies to patients faster." Good. Now Requirements: list each. Education: "Ph.D. in Pharmaceutical Sciences, Pharmacokinetics or related discipline, M.D with a Clinical Pharmacology expertise, or a Pharm D. with a Clinical Pharmacology fellowship" Experience: "10+ years of experience in biotech/pharmaceutical drug development." Demonstrated success leading all clinical pharmacology related aspects of drug development. Ability to work closely with internal and external stakeholders to manage PK, PK-PD, and PK-safety analyses, including non-compartmental analysis, population PK modeling, and PK-PD modeling and simulations to support dose selection, exposure-response and exposure-safety analyses through various phases of drug development. Proficiency with WinNonlin, Monolix, NONMEM, R or other modeling software. Effective skills directed toward driving collaboration, achieving results, influencing, and resolving conflicts across internal and external stakeholders Demonstrated experience responding to regulatory agency questions, preparing clinical pharmacology aspects of regulatory submissions and attending regulatory meetings. Highly motivated, decisive, and results-oriented individual who is proactive, resourceful, and efficient with the flexibility and creativity to excel in and contribute to a rapidly growing drug discovery and development company Experience in oncology is preferred, but not an absolute requirement. We need to ensure we keep the bullet points as