Executive Director, Clinical Business Operations

About the Role

As a global operational strategy and governance leader, drive operational excellence, financial stewardship, compliance, scalability, and digital transformation initiatives across the Clinical Business Operations team. Oversee investigator budgets, site contracts, site payments, and budget data hub team to ensure precise budget forecasting, efficient site contract execution, timely and accurate site payments, and budget data entry in databases. Responsible for CBO workforce planning, talent acquisition, succession planning, capability development, performance management, and fostering a high-performing, agile, and continuously improving team.

Responsibilities

• Ensure alignment of regional execution strategies with global governance frameworks, including clear accountability models, decision-making processes, and issue escalation mechanisms across cross-functional and cross-country stakeholders.
• Establish and lead recurring governance cadences, including quarterly business reviews, escalation forums, and executive reporting to ensure risks, trends, and operational performance are proactively managed and communicated.
• Own and monitor key operational and financial performance indicators (KPIs) across investigator budgeting, site contracting, payments, and budget data governance functions, including but not limited to:
  • Site contract cycle time and execution timeliness
  • Budget forecast accuracy and forecast vs. actual variance
  • Site payment timeliness and reconciliation accuracy
• Provide strategic oversight of investigator fee budget planning activities to support accurate financial forecasting.
• Direct the development, review, negotiation, and timely execution of site budgets and clinical trial agreements in alignment with Fair Market Value principles, study requirements, company standards, and study start-up timelines to support efficient operational delivery.
• Supervise the end-to-end site payment process and payment reconciliation process to ensure financial obligations are processed accurately and in accordance with contractual terms and payment schedules.
• Oversee the collection, validation, and maintenance of budget-related information within designated databases and systems to support data integrity and accuracy.
• Ensure all budget, contract, payment, and supporting operational documentation remains audit-ready and compliant with applicable regulatory, financial, and internal governance standards.
• Maintain oversight of Sunshine reporting obligations and global transparency requirements, ensuring appropriate processes, controls, and stakeholder alignment are consistently implemented across regions.
• Provide strategic oversight of outsourced vendors and external business partners, including performance monitoring, service quality oversight, issue escalation, and governance.
• Establish strong partnerships with Corporate Finance to drive financial governance, including oversight of accruals, forecast versus actual, and reconciliation processes.
• Oversee operational finances and team resources to ensure activities remain within approved budgets and resource allocations.
• Provide leadership, guidance, and performance management to team members, fostering accountability, collaboration, and continuous improvement.
• Support implementation of automation tools and digital solutions to improve overall productivity.

Requirements

• Bachelor’s degree or above in Life Sciences, Medical Science/Medical, Finance, Health Economics, or related fields.
• 14+ years of experience in Clinical Operations, or study start-up, clinical site budgets, clinical site contracts, within a pharmaceutical sponsor or CRO environment.
• 20+ years of experience preferred.
• Strong planning and organizational skills and the ability to effectively lead a team in a dynamic environment with competing priorities.
• Strong executive communication skills with the ability to present data-driven insights to Senior leadership.
• Solution-driven and results-focused, with a willingness to dive deep and take a hands-on approach to work.
• Demonstrated ability to analyze complex financial data and translate insights into actionable guidance.
• Experience working cross-functionally with Clinical Operations, Finance, Payments, and Legal stakeholders.
• Advanced proficiency in Excel and data analytics tools; experience with budget systems and contract lifecycle management platforms preferred.
• Good knowledge of ICH-GCP, pharmaceutical-related regulations, and laws.
• Proficiency in Microsoft Office apps, PowerBI, or equivalent, CTMS, Contract Lifecycle Management System, Veeva, SharePoint, etc.
• Travel required (10% globally).

Global Competencies

When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity, and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world.

• Fosters Teamwork
• Provides and Solicits Honest and Actionable Feedback
• Self-Awareness
• Acts Inclusively
• Demonstrates Initiative
• Entrepreneurial Mindset
• Continuous Learning
• Embraces Change
• Results-Oriented
• Analytical Thinking/Data Analysis
• Financial Excellence
• Communicates with Clarity

Pay

Salary Range: $271,800.00 - $351,800.00 annually. BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors unique to each candidate, including job-related skills, depth of experience, certifications, relevant education or training, and specific work location.

Benefits

• Annual bonus plan (non-commercial roles) or incentive compensation plan (commercial roles).
• Eligibility for discretionary equity awards and voluntary participation in the Employee Stock Purchase Plan.
• Comprehensive benefits package including:
  • Medical, Dental, and Vision coverage
  • 401(k) retirement plan
  • FSA/HSA options
  • Life Insurance
  • Paid Time Off
  • Wellness programs