Engineer II, Process safety

About the role

Join Takeda as an Engineer II, Process Safety. As part of the SMPD - Process Engineering & Technology team, you will report to the Associate Director of Process Engineering.

Responsibilities

• Support phase appropriate process safety testing.
• Work with process chemists and engineers to perform a thorough evaluation of all known and potential hazards for the safe scale-up of chemical processes for preparing pharmaceutical intermediates and active pharmaceutical ingredients in Takeda's research and manufacturing facilities.
• Collect and integrate relevant process safety data (e.g., calorimetry, pressure build-up, off-gassing), using for e.g. DSC, ARC, TSU, EasyMax, RC-1 and ARC into digital platforms for seamless data analysis and sharing, ensuring data complies with FAIR principles (Findable, Accessible, Interoperable, Reusable).
• Document and summarize safety results in an Electronic Lab Notebook (ELN) and generate comprehensive digital process safety reports, ensuring consistent and accessible data tracking and compliance documentation.
• Partner with internal & external manufacturing organizations to ensure the safe scale-up of Takeda's processes.
• Use software and build models to calculate critical process parameters, such as runaway reactions, self-accelerating decomposition temperature (SADT), and time to maximum rate under adiabatic conditions (TMRad), driving proactive safety interventions.
• Maintain SMPD's kilo labs, ensuring that they are safe, clean and functional.
• Manage the kilo lab inventory (including chemicals, reagents, equipment & consumables) and ensure adequate supplies are available.
• Coverage with contractors, vendors, and internal stakeholders to oversee the installation, commissioning, and qualification of kilo lab equipment and systems.
• Oversee internal manufacturing campaigns (e.g. reviews batch records, set-up equipment, support execution & cleaning).
• Support local initiatives as directed by his/her supervisor and participate in global functional initiatives as appropriate.

Requirements

• Associates degree in chemistry, biology, pharmacy, engineering or related pharmaceutical science and 2+ years relevant industry experience.
• Bachelor's degree in chemistry, biology, pharmacy, engineering or related pharmaceutical science; some relevant industry experience preferred.
• Previous experience working in a lab setting preferred.
• Previous experience working in a pilot plant setting a plus.
• Previous experience in process safety in the pharmaceutical, agrochemical, fine chemical or related industry a plus.
• Experience using relevant process safety equipment (e.g. DSC, RC1, Easymax HFCal, ARC, Tsu) a plus.
• Previous experience with software packages for process safety prediction (e.g., AKTS, Aspen Plus, gPROMS) a plus, focusing on the prediction of thermal, chemical, and kinetic properties.
• Understanding of FAIR data principles (Findable, Accessible, Interoperable, Reusable) to drive efficient data management for safety modeling and analytics.

Qualifications

• Associates degree in chemistry, biology, pharmacy, engineering or related pharmaceutical science and 2+ years relevant industry experience.
• Bachelor's degree in chemistry, biology, pharmacy, engineering or related pharmaceutical science; some relevant industry experience preferred.
• Previous experience working in a lab setting preferred.
• Previous experience working in a pilot plant setting a plus.
• Previous experience in process safety in the pharmaceutical, agrochemical, fine chemical or related industry a plus.
• Experience using relevant process safety equipment (e.g. DSC, RC1, Easymax HFCal, ARC, Tsu) a plus.
• Previous experience with software packages for process safety prediction (e.g., AKTS, Aspen Plus, gPROMS) a plus, focusing on the prediction of thermal, chemical, and kinetic properties.
• Understanding of FAIR data principles (Findable, Accessible, Interoperable, Reusable) to drive efficient data management for safety modeling and analytics.

Skills

• Experience using relevant process safety equipment (e.g. DSC, RC1, Easymax HFCal, ARC, Tsu).
• Previous experience with software packages for process safety prediction (e.g., AKTS, Aspen Plus, gPROMS).
• Understanding of FAIR data principles (Findable, Accessible, Interoperable, Reusable).

Benefits

Summary: We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. For Location: Boston, MA U.S. Base Salary Range : $71,800.00 - $112,860.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. EEO Statement: Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Locations: Boston, MA Worker Type: Employee Worker Sub-Type: Regular Time Type: Full time Job Exempt: Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.