Jobs · OTHR · Pennsylvania

Downstream Purification Scientist

Ecolab · King of Prussia, PA · 3 days ago
OTHR$97k–$145k/yrFull-time

About the role

Ecolab is seeking a Downstream Purification Scientist to develop chromatography processes and advance technical platforms that meet both business and customer needs. In this position, you will be responsible for conducting and leading chromatography experiments aimed at the industrial purification of monoclonal antibodies. You will collaborate closely with field and laboratory-based technical teams to design, execute, and communicate results from process development studies. We are looking for candidates who demonstrate strong collaboration and teamwork skills, are self-motivated, possess excellent communication abilities, are adept at creative problem-solving, and have keen observation and perception skills.

Responsibilities

  • Provide technical support by demonstrating strong theoretical and fundamental knowledge, in addition to practical applications, specifically chromatography, and other downstream unit operations, in general.
  • Routinely author protocols and reports for chromatography studies for purification of monoclonal antibodies.
  • Design, establish and execute bench-scale applications experiments using AKTA and other bench-scale chromatography systems.
  • Perform process screening and optimization experiments using a Tecan Te-Chrom high-throughput system.
  • Analyze samples using HPLC, SDS-PAGE, ELISA, PCR, spectrophotometry and other appropriate analytical tools to determine product purity and non-product related impurity profile.
  • Maintain accurate records and interpret data to provide detailed information and analysis on the execution of experiments.
  • Apply solid critical thinking skills with the ability to communicate technical issues, resolve complex problems and propose efficient and robust solutions.
  • Follow all procedures established in the lab to ensure efficiency and safety.
  • Must be able to lift up to 25 pounds at times.

Minimum Qualifications

  • BS required – Biochemistry, Chemical Engineering, Biotechnology, Biology, Chemistry or related degree
  • Five years of demonstrated experience in 'chromatography process development' for commercial scale purification of antibodies is a must-have.
  • Demonstrated strong theoretical and fundamental knowledge of chromatography
  • The ability to exhibit a high level of attention to detail and a quality-minded approach to all record keeping

Preferred Qualifications

  • MS in Biochemistry, Chemical Engineering, Biotechnology, Biology, Chemistry or related degree preferred
  • Ability to lead small lab-based teams preferred
  • Strong problem-solving skills
  • Strong oral and written communication skills
  • Understanding of fundamental physical/chemical properties and structural activity relationships
  • Working knowledge of statistics

Pay

The base salary range for this position is $96,700.00 - $145,100.00. This position is eligible for annual bonus pay based on performance, per plan terms. Many factors are taken into consideration when determining compensation, such as experience, education, training, geography, etc. We comply with all minimum wage and overtime laws.

Benefits

  • The opportunity to take on some of the world's most meaningful challenges, accelerating biologic drug development processes
  • The ability to make an impact and shape your career with a company that is passionate about growth
  • The support of an organization that believes it is vital to include and engage diverse people, perspectives and ideas to achieve our best

Ecolab strives to provide comprehensive and market-competitive benefits to meet the needs of our associates and their families. Details available at jobs.ecolab.com/working-here.

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