Director, US HEOR & RWE

Remote location, ideally NE corridor.

About the role

The US Director, HEOR & RWE will lead the design, execution, and communication of health, economic and outcomes research strategies supporting the company’s global metabolic health portfolio. This leader will generate high-quality real-world, clinical, and economic evidence to demonstrate product value to payers, providers, patients, and policymakers. The role requires expertise in value demonstration, real-world data (RWD), and outcomes modeling, as well as the ability to translate complex data into actionable insights for commercial and clinical decision-making.

Responsibilities

• HEOR & Evidence Generation Strategy
  • Develop and implement integrated global HEOR strategies to support pipeline and lifecycle management programs with a US launch focus
• Real-World Data & Value Communication
  • Lead development of US RWD strategies and partnerships with academic consortia, claims databases, and health systems to support value demonstration
  • Design and implement real-world data analyses to understand and articulate current patient demographics, treatment patterns, and outcomes
  • Develop AMCP value dossiers, economic modeling, narratives, and scientific publications to support value propositions
  • Serve as a key domain expert for payer engagement, providing evidence summaries and presentations that strengthen product positioning and formulary access
  • Engage and collaborate with external partners including payers, providers, and other access decision-makers to establish and maintain strong partnerships and gather insights
  • Lead the external dissemination of HEOR/RWE deliverables including publications, presentations, and professional conferences
  • Provide input to clinical development programs
• Partnerships & Cross-Functional Collaboration
  • Collaborate closely with partners on HEOR & RWE programs, ensuring coordinated evidence generation, cost-sharing, and data-sharing aligned to global commercialization goals
  • Represent HEOR in relevant governance meetings, advisory boards, and internal strategy sessions to shape business decisions through evidence-driven insight

Requirements

• PhD, PharmD, MPH, or Master’s in Health Economics, Outcomes Research, Epidemiology, or a related discipline
• 8–12 years of HEOR/RWE experience in biotech, pharmaceutical organizations, or consultancies with demonstrated success in pre-launch and commercialization phases
• Therapeutic area expertise in metabolic, endocrine, or cardiometabolic diseases strongly preferred
• Deep understanding of payer and evidence requirements in the U.S.
• Proficiency in RWD study design and analysis, and patient outcome measure development
• Proven ability to communicate complex data to non-technical audiences, including payers, regulators, and cross-functional business leaders
• Experience leading external collaborators, vendors, and cross-company joint HEOR initiatives
• Publication track record and presentation experience at peer-reviewed scientific meetings

Benefits

We have a unique culture, characterized by excellent teamwork and strong engagement across the organization. Making bonds is at the core of everything we do—from discovering and developing the best new peptide drugs for patients, to engaging with our partners or connecting with each other. We bond through curiosity and playfulness as a team, allowing ourselves to challenge common thinking and drive future innovation.

Pay

The anticipated base pay range for this position is $210,000 - $250,000.

About the company

Zealand Pharma A/S (Nasdaq: ZEAL) is a biotechnology company focused on the discovery and development of peptide-based medicines. More than 10 drug candidates invented by Zealand Pharma have advanced into clinical development, of which two have reached the market and three candidates are in late-stage development. The company has development partnerships with a number of pharma companies as well as commercial partnerships for its marketed products. Zealand Pharma was founded in 1998 and is headquartered in Copenhagen, Denmark, with a team in the U.S.