Jobs · Research · Massachusetts

Director, Theranostics and Radiation Science

AstraZeneca · Boston, MA · 4 wk ago
ResearchFull-time

Responsibilities

  • Optimize and review nuclear medicine imaging protocols, including quality control parameters, image acquisition and reconstruction, radiation dose determination, and protocol dose management.
  • Define requirements and technical support for imaging execution at clinical sites, ensuring proper implementation and adherence to study protocols.
  • Design and oversee quality control protocols, working with both internal teams and external partners for imaging review and processing.
  • Provide training, mentorship, and problem-solving support to internal and external clinical study teams to ensure study objectives are met.
  • Perform image-based, patient-specific dosimetry calculations (internal dosimetry, not external beam radiation therapy [EBRT]).
  • Collaborate with the Radiation Sciences team on imaging protocol optimization, ensuring alignment with best practices in QC, image acquisition, radiation dose management, and compliance with regulatory standards.
  • Support regulatory compliance efforts related to radioactive materials, staying current with guidelines from regulatory and professional organizations (e.g., SNMMI, NRC, and international regulatory bodies).
  • Contribute to research and discovery projects as needed, providing scientific and technical expertise to advance innovation in radiation sciences and molecular imaging.

Qualifications

  • BS degree in physical sciences, mathematics or other physical sciences followed by a graduate degree (M.S. or PhD) in medical physics, physics or related scientific disciplines.
  • Medical physics residency or Post Doctoral training with 5+ years of Industry and/or clinical experience (post residency).
  • Knowledge and Experience with personalized dosimetry for radiopharmaceuticals, experience with programs such as Olinda, MIM and other imaging and dosimetry packages is required.
  • Board certification is preferred but not required.
  • Prior industry experience is preferred but not required.
  • Experience with radiopharmaceuticals, Nuclear Medicine, SPECT and PET imaging techniques, reconstruction, and camera quality control procedures are preferred.
  • Strong concepts in radiation biology and radiation physics are preferred.
  • Advanced technical computer skills and thorough understanding of modern electronic infrastructures relevant to radiological imaging such as DICOM, PACS is required and, client/server architectures and image processing is preferred.
  • Understanding of imaging-related project needs as expressed in a clinical study protocol.
  • Experience with radioactive materials regulations or guidelines from regulatory organizations and professional organizations, (e.g. AAPM, SNMMI, NRC, and other country regulatory bodies).

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