Director, Tax Operations
About the role
Build Our Future Together At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Director of Tax Operations to own the day-to-day management of the company's global tax reporting and compliance functions for the US. Reporting to the Head of Tax Operations, the Director runs the operational execution of tax accounting (ASC 740), U.S. compliance, indirect taxes, SOX controls, audits, and the systems and data that support them. In this role you will modernize the tax operating model — embedding artificial intelligence (AI), automation, and analytics into everyday tax work while maintaining rigorous controls and human review. The Director coordinates with Tax Strategy counterparts on planning, technical positions, and shared or cross-functional work, and manages the U.S. and Ireland operations as a single, well-run team.
Responsibilities
- Manage ASC 740 tax accounting including provisions, reconciliations, financial statement disclosures, and external audit coordination
- Ensure SOX-compliant internal controls over tax reporting processes, including AI and automation-enabled workflows
- Oversee all U.S. federal, state, and international tax compliance, filings, payments, and audit-ready documentation
- Manage tax credits (R&D, orphan drug), indirect taxes (sales/use, property, excise), and tax audits/examinations
- Monitor and implement regulatory changes including OECD Pillar Two, U.S. CAM