Jobs · Management · Massachusetts

Director, Statistical Genetics

Bristol Myers Squibb · Cambridge, MA · 3 wk ago
Management$240k–$291k/yrFull-time

About the role

Bristol Myers Squibb seeks a talented statistical genetics expert to lead the Target Sciences team. This role will sit within Informatics & Predictive Sciences, a globally distributed group driving innovative computational research for discovery and early development within BMS research.

Responsibilities

  • Drive design and implementation of computational strategy to infer causal mechanisms driving disease using human genetics and other data types (e.g. Mendelian randomization with proteomics, TWAS, colocalization)
  • Lead team to perform cross-biobank analyses focused on identifying mechanisms underlying human genetic risk factors (e.g. LD score regression, eQTL mapping, scRNAseq)
  • Lead team and coordinate with stakeholders across research to facilitate the use of germline genetics for discovery in neuro, immunology, and cardiovascular disease
  • Evaluate and prioritize multi-modal, disease-specific datasets that will enable deep understanding of causal human biology of priority disease areas
  • Coordinate with stakeholders across research to nominate, evaluate, and advance novel drug targets
  • Communicate findings and recommend follow up actions in multiple settings (including 1:1, seminars, project meetings, and external publications)

Requirements

  • Bachelor’s Degree with 15+ years of academic / industry experience
  • Master’s Degree with 12+ years of academic / industry experience
  • PhD with 8+ years of academic / industry experience
  • 6+ years leadership experience

Qualifications

  • PhD in statistical genetics or a related computational/quantitative discipline field with 8+ or more years of relevant postdoctoral research and/or industry experience preferred
  • Experience in leading efforts to apply genetics to drug discovery
  • Deep scientific expertise in application of statistical genetic methods (GWAS, exWAS, Mendelian Randomizaiton, colocalization, polygenic risk scores)
  • Advanced hands-on knowledge of at least one high-level programming language such as R or Python
  • Familiarity with functional genomics preferred
  • Demonstrated ability to advance multi-disciplinary team projects
  • Managerial and mentorship experience in an industry setting

Benefits

Our benefits include: Health Coverage, wellbeing support, financial well-being and protection, work-life benefits, and more. For more details, visit careers.bms.com/life-at-bms/.

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