Director - Real World Data (RWD) Strategy - CMH

About the role

The Director, RWD Strategy serves as Lilly's enterprise champion for RWD in Cardiometabolic Health (CMH), translating the rapidly evolving external data landscape into a coherent, high-impact internal strategy that accelerates drug development, strengthens regulatory submissions, and maximizes the scientific and commercial return on Lilly's RWD investments.

Responsibilities

• Develop and drive the strategic vision for CMH RWD utilization across the product lifecycle, from early development through post-marketing and connecting opportunities across functions for maximizing RWD use for patient and Lilly impact and in close collaboration with enterprise-level RWD acquisitions.
• Create a systematic framework for quantifying the value delivered by RWD investments — in terms of regulatory impact, commercial value, publications, clinical development acceleration, or avoided costs.
• Define and track enterprise RWD performance KPIs to measure impact, improve decision making, and optimize RWD investments.
• Maintain a deep understanding of external landscape for RWD, knowledge of Lilly licensed RWD, and manage the inventory of RWD.
• Collaborate cross-functionally with key Lilly stakeholders (e.g. Medical Affairs, SDIA, BI&A, HEOR, Epidemiology, Lilly Value Access, Tech@Lilly, etc) to identify data gaps, redundancies and opportunities where RWD can inform decision making to avoid redundancy and improve ROI.
• Lead the identification, evaluation, acquisition and cross-BU coordination of fit-for-purpose, high-value CMH RWD sources, aligned with scientific and business needs that match RWD sources to research questions.
• Evaluate and operationalize federated learning partnerships, synthetic data use cases, and privacy-enhancing computation methods, in collaboration with Tech@Lilly and external data partners.
• Lead the development, communication, and adherence to RWD health information standards, tools and technology and processes for RWE generation, with a particular focus on leveraging RWD/E in regulatory decision.
• Develop strategy for integrating SDOH, patient-reported outcomes, digital/wearable biomarker, imaging, -omics data into Lilly's RWD infrastructure, with particular attention to health equity and diverse population representation in evidence generation.
• Drive greater value to the portfolio by delivering innovative RWD solutions (e.g. new applications of RWD), evaluating non-traditional sources of RWD and enabling and applying new RWD capabilities (e.g. tokenization of data).
• Access to and Maintenance of RWD Lead RFP processes for new data sources and coordinated data acquisition and usage.
• Exercise broad knowledge of data partners, procurement pathways, and business value to guide investment decisions.
• Promote consistent, transparent decisionmaking regarding source selection, contract terms, and portfolio priorities.
• Operationalize structured governance for RWD investments, participating in or supporting the RWD Steering Committee and other crossfunctional decision-right structures.
• Maintain current RWD information in the RWE business process and knowledge management solution, Pangaea and Data Marketplace.
• Continually seek and implement means of improving processes to reduce cycle time and decrease work effort to maximize the return of the investment (i.e., technology purchases, data strategies, etc.) of the RWE health information assets/domains managed.

Qualifications

• Advanced degree (PharmD, MD, PhD, MS, MSN, MPH) in a quantitative or health related field.
• Demonstrated ability to influence decision-making and network effectively to achieve cross-functional alignment.
• Strong analytic skills (e.g. ability to program in SAS, R, Python, etc).
• Experience in delivering innovative capabilities.
• Strong comprehension and communication skills, both written and verbal.
• Extensive experience (5+ years) working hands on with a wide range of RWD sources including selecting, evaluating or using RWD sources and healthcare data structure (claims, EMR, registry, multi-modal RWD – RNA, DNA, proteomics, imaging).
• Previous experience with broad and deep range of RWD partners and tools including matching sources to research questions across therapeutic areas and knowledge of procurement and business value to present ROI to teams.
• Excellent problem-solving and analytical skills.
• Experience developing or executing global or enterprise RWD strategy.