Director, Commercial Supply Chain
for sections: About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule. Only include sections that have real specific content. We must not repeat job title as heading. No Job ID etc. Remove boilerplate like EEO, legal, application instructions, etc. Must preserve all substantive information.
We need to parse the posting.
Key sections:
- Intro paragraph about uniQure mission etc. Could be "About the role" or maybe "About the role" includes description of role and mission. The posting starts: "At uniQure, we are delivering on the promise of gene therapy...". That's about company and role. Could be placed under About the role
.
- Then description of responsibilities: many bullet points under "Key Result Areas (major Duties, Accountabilities And Responsibilities)" with subheadings: Commercial Supply Chain Build & Scale, Launch Readiness, Demand & Supply Planning / S&OP, Distribution, Logistics & Cold Chain, Compliance, Quality & Risk, Cross-Functional Collaboration & Financial Partnership. Those are responsibilities. So we can put under Responsibilities
a - each duty. Could group but we need to preserve all substantive info. We can list each bullet as
- . Might need to keep subheadings? Not required but we can include them as part of li text.
- Qualifications & Skills: there is a section "Qualifications & Skills" with bullet list of qualifications. Also there is "Who You Are" which is more personal attributes; could be part of Skills or Qualifications? Could treat as Skills or maybe separate "Skills". The instruction: use headings for Skills, Qualifications, Benefits, Pay, Schedule. We have qualifications and skills content. Could combine into one section? But we have both headings available. We could put qualifications under
Qualifications
and skills under Skills
. However the posting lumps them together. We need to decide: we can split: Qualifications: education, years experience, direct experience, etc. Skills: knowledge of S&OP, financial acumen, ERP proficiency, communication, etc. The "Who You Are" could be under Skills or maybe under Qualities; but we can include under Skills as personal attributes.
- Benefits: Not mentioned explicitly. There's no benefits description. So we should not create Benefits section.
- Pay: There's salary range: "US Salary Range $205,000—$265,000 USD". Also mention that actual base salary may depend... That's pay info. So we should include Pay section with that info.
- Schedule: Not mentioned. No schedule info. So omit.
We must not include placeholder text like "commensurate with experience". The salary range is specific, so we include.
We must not include boilerplate like EEO, equal opportunity, accommodation, privacy notice, etc. Remove those.
We must preserve all substantive information: So we need to keep the mission intro, responsibilities details, qualifications, skills, who you are, salary range.
We need to format as HTML fragment: only use , - ,
. No /. No markdown.
We must not repeat job title as heading. The job title is "Director, Commercial Supply Chain". Not to be used as heading.
We need to ensure we don't include any headings with empty content.
Let's craft.
First, About the role: combine the introductory paragraphs up to "As a foundational hire within Global Operations, you will stand up the people, processes, systems, and external partnerships required to deliver complex, high-value, temperature-sensitive therapies reliably and compliantly to treatment centers and patients worldwide." plus maybe the preceding sentences about mission and role. We'll include all that as prose in
.
Then Responsibilities: we need to list each duty. The posting has headings within responsibilities: Commercial Supply Chain Build & Scale, Launch Readiness, Demand & Supply Planning / S&OP, Distribution, Logistics & Cold Chain, Compliance, Quality & Risk, Cross-Functional Collaboration & Financial Partnership. Under each there are bullet points (some are sentences). We'll extract each bullet as
- . We'll keep the substance.
Let's extract:
Under Commercial Supply Chain Build & Scale:
- Design and stand up the commercial supply chain operating model, processes, tools, governance, and organization, fit for a low-volume, high-value AAV gene therapy portfolio
- Define and execute a phased roadmap that scales capability from initial launch to a repeatable, multi-product, multi-market operation
- Build and lead the commercial supply chain team over time, fostering a performance-driven, patient-focused, continuous-improvement culture
- Balance strategic build with hands-on execution, personally owning critical tactical activities until the function is scaled
Launch Readiness (Phase 3 -> Global Commercial Launch):
- Drive supply chain strategy and readiness for the Phase 3 program and subsequent global commercial launch, including new markets, indications, and lifecycle expansions
- Develop launch supply plans, network design, and readiness checklists in alignment with product lifecycle management, in partnership with TechOps, QA, RA, Clinical Operations and Commercial
- Establish launch governance and cross-functional alignment, serving as the supply chain single point of contact to product and launch teams
- Ensure treatment-center and channel readiness, including qualification of specialty distribution and treatment-site onboarding for gene therapy administration
Demand & Supply Planning / S&OP:
- Establish and run demand and supply planning and the S&OP/IBP process for the commercial portfolio, managing the lumpy, patient-driven demand characteristic of gene therapy
- Translate commercial demand signals and market events into actionable, financially sound supply plans; improve forecast accuracy to support reliable supply and inventory management
- Manage constrained, high-value inventory and CDMO capacity, leading allocation, scenario planning, and trade-off decisions to protect product availability
- Partner with Finance on forecast assumptions, inventory implications, accruals, budget alignment, and performance follow-up
Distribution, Logistics & Cold Chain:
- Define and optimize the global distribution network - 3PLs, specialty distributors/pharmacies, and treatment centers - to meet market access models and patient needs
- Own end-to-end cold-/ultra-cold-chain logistics, ensuring temperature integrity, chain of custody, and last-mile delivery to treatment sites across regions
- Establish import/export, and returns processes in line with uniQure standards and local market requirements
- Own product availability, service levels (OTIF), and inventory performance for the commercial market(s)
Compliance, Quality & Risk:
- Ensure full compliance with GDP, DSCSA/serialization, EU FMD, and applicable global regulatory requirements across the distribution network
- Partner with Quality to maintain GxP/GDP compliance, including exception handling, deviations, root-cause investigations, CAPA closure, and KPI/QMR reporting
- Lead supply risk assessment, business continuity, and mitigation (including contingency and dual-source thinking for critical nodes) and act as the escalation point for critical supply, service, and distribution issues
Cross-Functional Collaboration & Financial Partnership:
- Serve as the commercial supply chain partner to Commercial (Sales, Marketing, Market Access, Patient Services), TechOps, Quality, Regulatory, Finance, and Legal
- Provide executive-level insight on supply risks, trade-offs, and scenario planning to inform corporate decision-making
- Manage external partners (CDMOs, 3PLs, logistics providers) against clear performance expectations and total-cost-of-ownership views
Now Qualifications & Skills section: bullet list:
- Bachelor’s degree in Supply Chain, Engineering, Life Sciences, or related field (or equivalent experience); advanced degree a plus
- Approximately 8-10 years of progressive commercial supply chain experience in biopharma/life sciences, including direct experience leading product launches
- Direct experience in cell and gene therapy, biologics, or other complex/cold-chain, low-volume high-value modalities strongly preferred
- Proven ability to build or significantly scale a commercial supply chain capability, ideally in an emerging or mid-size company, in a predominantly outsourced (CDMO/3PL) environment
- Strong knowledge of S&OP/IBP, demand and supply planning, inventory management, and distribution network strategy
- Deep understanding of pharmaceutical distribution models, specialty distribution/pharmacy, 3PLs and of GDP/DSCSA/serialization-regulated environments; treatment-center/site logistics for advanced therapies advantageous
- Experience operating across both global and market-specific (e.g., US and/or EU) supply chains
- Strong financial acumen: forecasting, budgeting, inventory economics, and partnership with Finance
- Proficiency with planning and ERP systems (e.g., SAP, Anaplan, or equivalent)
- Demonstrated willingness and ability to operate hands-on across both tactical execution and strategic leadership
- Excellent communication and stakeholder-management skills; proven ability to lead through complexity and influence senior stakeholders and external partners
Then "Who You Are": bullet list:
- You are genuinely passionate about uniQure’s mission to transform patients’ lives through innovative gene therapies
- You are comfortable spanning strategy and execution, and you take pride in doing the hands-on work needed to build something from the ground up
- You bring precision, excellence, and a rooted-in-science approach to problem-solving
- You are a generous collaborator who works well across functions and with external partners
- You can grapple with ambiguity and the unknown, and you are energized by a fast-growing, dynamic environment
We could treat these as Skills or maybe as part of Skills. Since we have Skills heading, we can include these under Skills as well. But we already have many skill bullets. Could combine all under Skills. However we have Qualifications heading for degree/experience etc. We'll put qualifications under
Qualifications
and skills under Skills
. For Skills we will include the knowledge, financial acumen, ERP proficiency, communication, plus the "Who You Are" personal attributes.
Now Pay: we have salary range and description. We'll put under Pay
a with the salary range and note that actual base salary may depend on qualifications etc. But we must not include boilerplate like "The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location." That's still substantive? It's generic but maybe considered boilerplate. The instruction: remove cookie/navigation/legal/EEO/equal-opportunity/scam-warning boilerplate, duplicated lines, and application instructions. The sentence about minimum wage might be considered boilerplate but it's still part of pay description. Might be safe to keep? It's not EEO etc. It's a standard statement. I'd keep it as it's part of pay info. However the instruction says "Preserve ALL substantive information; do NOT invent or summarize away detail." So we should keep that sentence. It's not boilerplate per se. It's about compensation compliance. Keep.
Also the line: "The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant, relevant years of experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from where they will be performing the job." That's substantive. Keep.
Now we must not include the EEO paragraph, accommodation request, privacy notice, etc. Remove those.
Now produce HTML.
Structure:
About the role
... (intro paragraphs)
Responsibilities
- ... each duty
...
Qualifications
- ... each qualification bullet
...
Skills
- ... each skill bullet (including knowledge, financial acumen, ERP proficiency, communication, and Who You Are bullets)
...
Pay
... salary range paragraph(s)
No Benefits, Schedule.
Make sure no extra whitespace issues.
Now craft the About the role paragraph: combine the first few paragraphs
Qualifications
and skills underSkills
. However the posting lumps them together. We need to decide: we can split: Qualifications: education, years experience, direct experience, etc. Skills: knowledge of S&OP, financial acumen, ERP proficiency, communication, etc. The "Who You Are" could be under Skills or maybe under Qualities; but we can include under Skills as personal attributes. - Benefits: Not mentioned explicitly. There's no benefits description. So we should not create Benefits section. - Pay: There's salary range: "US Salary Range $205,000—$265,000 USD". Also mention that actual base salary may depend... That's pay info. So we should include Pay section with that info. - Schedule: Not mentioned. No schedule info. So omit. We must not include placeholder text like "commensurate with experience". The salary range is specific, so we include. We must not include boilerplate like EEO, equal opportunity, accommodation, privacy notice, etc. Remove those. We must preserve all substantive information: So we need to keep the mission intro, responsibilities details, qualifications, skills, who you are, salary range. We need to format as HTML fragment: only use, - ,
. No /. No markdown.
We must not repeat job title as heading. The job title is "Director, Commercial Supply Chain". Not to be used as heading.
We need to ensure we don't include any headings with empty content.
Let's craft.
First, About the role: combine the introductory paragraphs up to "As a foundational hire within Global Operations, you will stand up the people, processes, systems, and external partnerships required to deliver complex, high-value, temperature-sensitive therapies reliably and compliantly to treatment centers and patients worldwide." plus maybe the preceding sentences about mission and role. We'll include all that as prose in
.
Then Responsibilities: we need to list each duty. The posting has headings within responsibilities: Commercial Supply Chain Build & Scale, Launch Readiness, Demand & Supply Planning / S&OP, Distribution, Logistics & Cold Chain, Compliance, Quality & Risk, Cross-Functional Collaboration & Financial Partnership. Under each there are bullet points (some are sentences). We'll extract each bullet as
- . We'll keep the substance.
Let's extract:
Under Commercial Supply Chain Build & Scale:
- Design and stand up the commercial supply chain operating model, processes, tools, governance, and organization, fit for a low-volume, high-value AAV gene therapy portfolio
- Define and execute a phased roadmap that scales capability from initial launch to a repeatable, multi-product, multi-market operation
- Build and lead the commercial supply chain team over time, fostering a performance-driven, patient-focused, continuous-improvement culture
- Balance strategic build with hands-on execution, personally owning critical tactical activities until the function is scaled
Launch Readiness (Phase 3 -> Global Commercial Launch):
- Drive supply chain strategy and readiness for the Phase 3 program and subsequent global commercial launch, including new markets, indications, and lifecycle expansions
- Develop launch supply plans, network design, and readiness checklists in alignment with product lifecycle management, in partnership with TechOps, QA, RA, Clinical Operations and Commercial
- Establish launch governance and cross-functional alignment, serving as the supply chain single point of contact to product and launch teams
- Ensure treatment-center and channel readiness, including qualification of specialty distribution and treatment-site onboarding for gene therapy administration
Demand & Supply Planning / S&OP:
- Establish and run demand and supply planning and the S&OP/IBP process for the commercial portfolio, managing the lumpy, patient-driven demand characteristic of gene therapy
- Translate commercial demand signals and market events into actionable, financially sound supply plans; improve forecast accuracy to support reliable supply and inventory management
- Manage constrained, high-value inventory and CDMO capacity, leading allocation, scenario planning, and trade-off decisions to protect product availability
- Partner with Finance on forecast assumptions, inventory implications, accruals, budget alignment, and performance follow-up
Distribution, Logistics & Cold Chain:
- Define and optimize the global distribution network - 3PLs, specialty distributors/pharmacies, and treatment centers - to meet market access models and patient needs
- Own end-to-end cold-/ultra-cold-chain logistics, ensuring temperature integrity, chain of custody, and last-mile delivery to treatment sites across regions
- Establish import/export, and returns processes in line with uniQure standards and local market requirements
- Own product availability, service levels (OTIF), and inventory performance for the commercial market(s)
Compliance, Quality & Risk:
- Ensure full compliance with GDP, DSCSA/serialization, EU FMD, and applicable global regulatory requirements across the distribution network
- Partner with Quality to maintain GxP/GDP compliance, including exception handling, deviations, root-cause investigations, CAPA closure, and KPI/QMR reporting
- Lead supply risk assessment, business continuity, and mitigation (including contingency and dual-source thinking for critical nodes) and act as the escalation point for critical supply, service, and distribution issues
Cross-Functional Collaboration & Financial Partnership:
- Serve as the commercial supply chain partner to Commercial (Sales, Marketing, Market Access, Patient Services), TechOps, Quality, Regulatory, Finance, and Legal
- Provide executive-level insight on supply risks, trade-offs, and scenario planning to inform corporate decision-making
- Manage external partners (CDMOs, 3PLs, logistics providers) against clear performance expectations and total-cost-of-ownership views
Now Qualifications & Skills section: bullet list:
- Bachelor’s degree in Supply Chain, Engineering, Life Sciences, or related field (or equivalent experience); advanced degree a plus
- Approximately 8-10 years of progressive commercial supply chain experience in biopharma/life sciences, including direct experience leading product launches
- Direct experience in cell and gene therapy, biologics, or other complex/cold-chain, low-volume high-value modalities strongly preferred
- Proven ability to build or significantly scale a commercial supply chain capability, ideally in an emerging or mid-size company, in a predominantly outsourced (CDMO/3PL) environment
- Strong knowledge of S&OP/IBP, demand and supply planning, inventory management, and distribution network strategy
- Deep understanding of pharmaceutical distribution models, specialty distribution/pharmacy, 3PLs and of GDP/DSCSA/serialization-regulated environments; treatment-center/site logistics for advanced therapies advantageous
- Experience operating across both global and market-specific (e.g., US and/or EU) supply chains
- Strong financial acumen: forecasting, budgeting, inventory economics, and partnership with Finance
- Proficiency with planning and ERP systems (e.g., SAP, Anaplan, or equivalent)
- Demonstrated willingness and ability to operate hands-on across both tactical execution and strategic leadership
- Excellent communication and stakeholder-management skills; proven ability to lead through complexity and influence senior stakeholders and external partners
Then "Who You Are": bullet list:
- You are genuinely passionate about uniQure’s mission to transform patients’ lives through innovative gene therapies
- You are comfortable spanning strategy and execution, and you take pride in doing the hands-on work needed to build something from the ground up
- You bring precision, excellence, and a rooted-in-science approach to problem-solving
- You are a generous collaborator who works well across functions and with external partners
- You can grapple with ambiguity and the unknown, and you are energized by a fast-growing, dynamic environment
We could treat these as Skills or maybe as part of Skills. Since we have Skills heading, we can include these under Skills as well. But we already have many skill bullets. Could combine all under Skills. However we have Qualifications heading for degree/experience etc. We'll put qualifications under
Qualifications
and skills under Skills
. For Skills we will include the knowledge, financial acumen, ERP proficiency, communication, plus the "Who You Are" personal attributes.
Now Pay: we have salary range and description. We'll put under Pay
a with the salary range and note that actual base salary may depend on qualifications etc. But we must not include boilerplate like "The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location." That's still substantive? It's generic but maybe considered boilerplate. The instruction: remove cookie/navigation/legal/EEO/equal-opportunity/scam-warning boilerplate, duplicated lines, and application instructions. The sentence about minimum wage might be considered boilerplate but it's still part of pay description. Might be safe to keep? It's not EEO etc. It's a standard statement. I'd keep it as it's part of pay info. However the instruction says "Preserve ALL substantive information; do NOT invent or summarize away detail." So we should keep that sentence. It's not boilerplate per se. It's about compensation compliance. Keep.
Also the line: "The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant, relevant years of experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from where they will be performing the job." That's substantive. Keep.
Now we must not include the EEO paragraph, accommodation request, privacy notice, etc. Remove those.
Now produce HTML.
Structure:
About the role
... (intro paragraphs)
Responsibilities
- ... each duty
...
Qualifications
- ... each qualification bullet
...
Skills
- ... each skill bullet (including knowledge, financial acumen, ERP proficiency, communication, and Who You Are bullets)
...
Pay
... salary range paragraph(s)
No Benefits, Schedule.
Make sure no extra whitespace issues.
Now craft the About the role paragraph: combine the first few paragraphs
. No /. No markdown. We must not repeat job title as heading. The job title is "Director, Commercial Supply Chain". Not to be used as heading. We need to ensure we don't include any headings with empty content. Let's craft. First, About the role: combine the introductory paragraphs up to "As a foundational hire within Global Operations, you will stand up the people, processes, systems, and external partnerships required to deliver complex, high-value, temperature-sensitive therapies reliably and compliantly to treatment centers and patients worldwide." plus maybe the preceding sentences about mission and role. We'll include all that as prose in
. Then Responsibilities: we need to list each duty. The posting has headings within responsibilities: Commercial Supply Chain Build & Scale, Launch Readiness, Demand & Supply Planning / S&OP, Distribution, Logistics & Cold Chain, Compliance, Quality & Risk, Cross-Functional Collaboration & Financial Partnership. Under each there are bullet points (some are sentences). We'll extract each bullet as
Qualifications
and skills underSkills
. For Skills we will include the knowledge, financial acumen, ERP proficiency, communication, plus the "Who You Are" personal attributes. Now Pay: we have salary range and description. We'll put underPay
awith the salary range and note that actual base salary may depend on qualifications etc. But we must not include boilerplate like "The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location." That's still substantive? It's generic but maybe considered boilerplate. The instruction: remove cookie/navigation/legal/EEO/equal-opportunity/scam-warning boilerplate, duplicated lines, and application instructions. The sentence about minimum wage might be considered boilerplate but it's still part of pay description. Might be safe to keep? It's not EEO etc. It's a standard statement. I'd keep it as it's part of pay info. However the instruction says "Preserve ALL substantive information; do NOT invent or summarize away detail." So we should keep that sentence. It's not boilerplate per se. It's about compensation compliance. Keep. Also the line: "The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant, relevant years of experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from where they will be performing the job." That's substantive. Keep. Now we must not include the EEO paragraph, accommodation request, privacy notice, etc. Remove those. Now produce HTML. Structure:
About the role
... (intro paragraphs)
Responsibilities
- ... each duty ...
Qualifications
- ... each qualification bullet ...
Skills
- ... each skill bullet (including knowledge, financial acumen, ERP proficiency, communication, and Who You Are bullets) ...
Pay
... salary range paragraph(s)
No Benefits, Schedule. Make sure no extra whitespace issues. Now craft the About the role paragraph: combine the first few paragraphs