Director, Commercial Supply Chain

About IDEAYA Biosciences: IDEAYA is a precision medicine oncology company committed to the discovery, development, and commercialization of transformative therapies for cancer. Our approach integrates expertise in small-molecule drug discovery, structural biology and bioinformatics with robust internal capabilities in identifying and validating translational biomarkers to develop tailored, potentially first-in-class targeted therapies aligned to the genetic drivers of disease. We have built a deep pipeline of product candidates focused on synthetic lethality and antibody-drug conjugates, or ADCs, for molecularly defined solid tumor indications. Our mission is to bring forth the next wave of precision oncology therapies that are more selective, more effective, and deeply personalized with the goal of altering the course of disease and improving clinical outcomes for patients with cancer.

When you're at IDEAYA, you will be in the midst of brilliant minds working on precision medicine therapies to help cancer patients. We are passionate and committed about being on the forefront of oncology medicine, which means we all have a high internal drive that is at the core of every person at IDEAYA. We are inquisitive, ask deep questions, and are data-driven innovators who like to collaborate and use teamwork to move science forward.

Location: South San Francisco, CA. This position reports to the Vice President, Clinical and Commercial Supply Chain and is based in our South San Francisco headquarters, requiring onsite presence four days per week per company policy.

About the role

We are seeking an experienced, strategic, resourceful, and highly motivated Director, Commercial Supply Chain to lead end-to-end commercial supply planning and operational launch readiness for IDEAYA Biosciences’ first commercial product, Darovasertib. This role ensures product availability, compliant distribution, and robust performance management. The ideal candidate will be a collaborative leader and critical thinker who can operate with autonomy, manage complex drug supply chains, and translate commercial demand forecasts into actionable supply strategies.

Responsibilities

• Own commercial supply strategy and launch readiness plans, ensuring supply chain readiness for launch and lifecycle supply.
• Develop and maintain integrated demand/supply plans, production schedules, capacity models, inventory strategy, and scenario analyses.
• Lead/drive S&OP cadence: monthly supply reviews, risk/opportunity assessments, mitigation actions, and executive-ready reporting.
• Lead end-to-end inventory management (GxP and SOX compliant) across the commercial supply chain, including inventory policy setting, reconciliation, cycle counting oversight, expiry tracking, and alignment with demand and production plans. System business owner for NetSuite Inventory Module.
• Manage external network execution; align campaign plans and batch execution to forecasts and contractual commitments.
• Partner with Finance/Accounting for reconciliations, chargebacks, rebates, etc.
• Oversee commercial packaging readiness: secondary packaging/labeling, serialization strategy/execution, artwork lifecycle coordination, shipping lane validation, cold-chain controls, and exception management.
• Serve as the primary point of contact for commercial packaging, labeling, logistics, and storage vendors and develop a governance process for effective management of these vendors.
• Build and monitor KPIs/dashboards (service level, plan adherence, capacity utilization, inventory health) and lead continuous improvement of planning tools/processes.
• Partner with Quality/Regulatory/CMC to ensure GxP-compliant release and distribution readiness and alignment to registration timelines.
• Support budgeting/forecasting for commercial supply activities, including scenario-based financial impact modeling.

Requirements

• BA/BS in Supply Chain, Engineering, Life Sciences (advanced degree preferred).
• 10–12+ years in biotech/pharma supply chain, including 3+ years commercial and/or late-stage launch readiness experience.
• Experience serving as a California Board of Pharmacy–designated representative (DR) for manufacturer, wholesaler, or distributor licensing, or eligibility and willingness to serve in this role.
• Proven experience managing external manufacturing and supply partners.
• Strong understanding of GMP/GDP, regulatory timing impacts on supply, and global distribution logistics.
• Advanced planning/analytics skills (Excel and/or supply planning tools); strong cross-functional leadership and communication.
• Comfortable operating in ambiguity; able to build processes “from the ground up”.
• Proficiency in Microsoft Office Suite and experience with collaborative platforms (e.g., SharePoint, Box) and NetSuite inventory systems.
• Willingness and ability to travel domestically and internationally as needed.

The successful candidate will be a team player with integrity, a commitment to quality, and the ability to think critically and creatively in a fast-paced, changing environment. All employees are expected to act with integrity and in full compliance with applicable laws, regulations, and IDEAYA policies, including IDEAYA’s Code of Conduct.

Benefits

• Comprehensive medical/dental/vision coverage (100% company paid for employees and 90% company paid for dependents).
• 401k and Employee Stock Purchase Plan (ESPP).
• Wellness programs.
• Company discretionary short-term incentive plan participation and stock option awards (based on board approval).

Pay

The expected salary range for the role of Director, Commercial Supply Chain is $203,000 - $251,000. The final salary offered will depend on factors such as office location, experience, education, and performance during the interview process.

Schedule

This position requires onsite presence in South San Francisco four days per week. Work-from-home flexibility is available for the remaining day. The Company requires all employees working in its facilities to be fully vaccinated from COVID-19, subject to reasonable accommodations for medical or religious reasons, and/or as otherwise required by applicable law.