Jobs · Analyst · Massachusetts

Clinical Trial Associate

Repertoire Immune Medicines · Cambridge, MA · 4 wk ago
On-siteAnalyst$62k–$86k/yrFull-time

Position Summary

Repertoire Immune Medicines is seeking a highly motivated Clinical Trial Associate (CTA) to join our Clinical Operations team and support the execution of early-phase oncology clinical trials. The CTA will provide critical operational support in execution of clinical trials across trial start-up, conduct, maintenance, and close-out activities. In this role, the CTA will work closely with the Director of Clinical Operations and the Clinical Trial Manager, cross-functional team members, CROs, vendors, and clinical sites to help ensure timely, high-quality operational execution of clinical trial activities in compliance with ICH-GCP, applicable FDA and global regulatory requirements, GDPR/HIPAA where relevant, and Repertoire SOPs.

Key Responsibilities

  • Support operational full life cycle execution of early-phase oncology clinical trials in accordance with protocol requirements, ICH-GCP, applicable global regulations, and company SOPs.

  • Capture and coordinate trial activities across multiple functional areas, CROs, vendors, and clinical sites to support timely execution of trial deliverables and milestones.

  • Identify operational issues, assess potential impact to trial timelines or compliance, and escalate risks or mitigation recommendations to Clinical Operations leadership as appropriate.

  • Support site activation, readiness for investigational product release, trial supply coordination, and issue resolution activities.

  • Maintain trial trackers, distribution lists, reports, and clinical systems.

  • Track trial progress, including key milestones, vendor deliverables, enrollment, monitoring activities, and trial action items.

  • Manage, organize, and maintain trial documentation to support inspection readiness and perform TMF quality checks including identification and resolution of documentation gaps, inconsistencies, and compliance risks.

  • Support preparation, review, tracking, and maintenance of regulatory and IRB/IEC documentation in collaboration with internal and external stakeholders.

  • Support audit and inspection readiness activities, including document retrieval, issue tracking, and follow-up coordination.

  • Track protocol deviations, operational issues, and compliance concerns, including escalation of significant risks to trial leadership.

  • Serve as an operational contact for CROs, vendors, and clinical sites under the direction of Clinical Trial Manager.

  • Coordinate trial meetings, prepare agendas and minutes, document key decisions and action items, and support timely follow-up and resolution of operational priorities.

  • Coordinate exchange of trial information and materials across cross-functional stakeholders to support execution and inspection readiness.

  • Exercise independent judgment in prioritizing competing operational activities and managing multiple trial deliverables.

Qualifications

  • Bachelor’s degree in life sciences, health sciences, nursing, public health, or related field.

  • Minimum of 2 years of experience supporting clinical operations, clinical research, or clinical trial execution activities.

  • Working knowledge of ICH-GCP, FDA regulations, and clinical trial processes within a biotech, sponsor, CRO, or research environment.

  • Experience with clinical systems and tools such as eTMF, EDC, CTMS, Smartsheet, Box, and Microsoft Office applications.

  • Strong organizational, analytical, and problem-solving skills with demonstrated ability to prioritize competing activities and manage multiple deliverables.

  • Ability to identify operational risks, support issue resolution, and escalate quality or compliance concerns appropriately.

  • Strong communication and cross-functional collaboration skills with internal and external stakeholders.

  • Experience supporting oncology or early-phase clinical trials is preferred.

Pay

The base salary for this role ranges from $62,000 to $86,000 and is determined based on a candidate’s skills, experience, and internal equity. In addition to a competitive base salary, Repertoire offers a broad range of benefits designed to attract, retain, and motivate top talent, including medical, dental, vision, and life insurance, flexible time off, a 401(k) retirement plan, and short- and long-term incentive opportunities.

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