Clinical Program Director – Precision Oncology Diagnostics (MRD Focus)

Job Summary

This role exists to design, execute, and scale clinical development programs that demonstrate the clinical utility of precision oncology diagnostics, with an initial and primary focus on molecular residual disease (MRD) in solid tumors. The purpose of this position is to ensure that diagnostic-driven evidence generation is tightly aligned with real-world clinical decision-making, guideline development, reimbursement needs, and long-term portfolio strategy.

Job Responsibilities

• Evaluate the current precision oncology and diagnostic evidence landscape to identify gaps limiting clinical adoption, guideline inclusion, reimbursement, and commercial scalability.
• Define diagnostic-focused clinical development priorities that demonstrate clear clinical utility, real-world impact, and value of MRD and other precision oncology assays.
• Develop and articulate a clear business and clinical rationale for proposed studies, linking evidence generation to strategic objectives, portfolio differentiation, and downstream impact.
• Partner with cross-functional teams, including medical affairs, market access, R&D, and commercial teams to ensure studies are designed to answer payer-, provider-, and health system–relevant questions.
• Ensure alignment between diagnostic capabilities, intended clinical use, and evolving standards of care.
• Lead the development of clinical study concepts, objectives, and endpoints, with a strong emphasis on MRD, ctDNA, and solid tumor applications.
• Drive protocol development in collaboration with medical affairs, R&D, regulatory, operations, and external partners.
• Actively manage ongoing studies, including oversight of timelines, enrollment progress, data quality, and operational execution.
• Ensure studies are fit-for-purpose and adaptable as scientific and clinical understanding and portfolio needs evolve.
• Serve as a scientific and clinical subject matter expert for MRD landscape and diagnostic-driven oncology studies in solid tumors.
• Lead and influence cross-functional working groups across medical affairs, operations, regulatory, market access, commercial, and laboratory teams to develop and deliver compelling medical communications regarding Labcorp Oncology diagnostics.
• Integrate field-based clinical and market access insights into internal development and operational teams to develop prospective, observational studies that are grounded in real-world clinical practice.
• Ensure diagnostic study designs clearly link test results to downstream clinical decisions, treatment selection, and patient outcomes.
• Collaborate closely with laboratory and assay development teams to ensure clinical studies reflect analytical and technical realities of testing.
• Establish and manage relationships with academic collaborators, research consortia, and partners.
• Support investigator selection, engagement, and ongoing collaboration to ensure high-quality study execution.
• Coordinate investigator meetings with partners to ensure the timely execution of study milestones.
• Represent the organization in external scientific forums, including investigator meetings, advisory boards, and major oncology conferences.
• Lead and contribute to abstracts, posters, manuscripts, and white papers that communicate clinical utility and real-world value.
• Translate complex genomic and diagnostic data into clear narratives for clinicians, payers, internal stakeholders, and partners.
• Partner with medical affairs, marketing, and communication teams to ensure compliant, consistent messaging across scientific and educational channels.
• Support internal regulatory strategy and, as needed, participate in interactions with regulatory authorities (e.g., FDA, EMA).
• Ensure all clinical activities are conducted in compliance with GCP, applicable regulations, and internal quality standards.
• Act as a foundational leader for the clinical development function within Labcorp and precision oncology portfolio.
• Define scalable processes, governance, and best practices for diagnostic-driven evidence generation.
• Contribute to hiring strategy, role definition, onboarding, and mentoring as the clinical development organization expands.

Minimum Qualifications

• Master’s degree in Certified Genetic Counseling
• 5 or more years of clinical experience in academia or oncology industry
• 3 or more years of experience in clinical development, clinical utility studies, and/or real-world evidence generation.

Preferred Qualifications

• Doctorate in Philosophy (PhD) or Pharmacy (PharmD) in Oncology
• 3 or more years of experience with clinical trial execution, including protocol development, site engagement, and data management
• 3 or more years of involvement in regulatory strategy or health authority interactions
• 3 or more years’ experience working as a Scientific Liaison or Oncology Research Partner

Additional Job Standards

• Experience in precision oncology diagnostics with a focus on solid tumors
• Experience in clinical development, clinical utility studies or real-world evidence generation experience should include diagnostics-driven experience
• Leadership experience should include autonomous leadership across cross-functional areas including medical, laboratory, regulatory, market access and commercial teams
• Preferred experience in clinical trials should include protocol development, site engagement and data management
• Preferred experience as a Scientific Liaison or Research Partner should be working with academic investigators and oncology research consortia
• Travel is expected for meetings, conferences, and key internal collaborations