Clinical Engagement Regional Associate Director (Americas)

Beeline Medicines is a clinical-stage biotechnology company focused on developing and delivering category-leading precision therapies to transform the lives of people living with autoimmune and inflammatory diseases. With a portfolio of potential best-in-class and first-in-disease therapeutic candidates, Beeline is advancing medicines that directly target key pathways governing dysregulated immunological and inflammatory responses, aiming to provide durable, life-changing impact for patients.

About the role

The Clinical Engagement Regional Associate Director is a field-based, senior-level, people-management role responsible for leading a team of Clinical Engagement Leads (CELs) who build and manage investigator and site relationships across the organization’s clinical trial portfolio. This role serves as the central global people manager for the field-based clinical engagement function in assigned region(s), combining people leadership with deep knowledge of the immunology and inflammation (I&I) therapeutic area and clinical trial operations. The position acts as the escalation point for complex investigator and site issues and as the primary conduit of field intelligence and team performance to senior Clinical Development and Medical Affairs leadership.

This is a highly visible role requiring the ability to build and lead a high-performing field team while operating independently across a broad assigned geography. The position is field-based, with regular travel within the designated territory and occasional travel outside the region for company meetings, training, or other events. Territory assignments may change based on business needs.

Responsibilities

• Provide day-to-day people leadership for a team of Clinical Engagement Leads, including coaching, performance management, goal-setting, and career development to build and sustain a high-performing field-based engagement team.
• Support site engagement strategy and priorities for the assigned region/country, translating clinical program goals into team-level objectives for investigator identification, site feasibility, activation, and enrollment performance.
• Recruit, onboard, and develop Clinical Engagement Lead talent in partnership with HR and Clinical Operations leadership on hiring decisions, territory/portfolio assignments, and ongoing skills development.
• Review and approve site engagement plans and feasibility recommendations developed by the team, providing strategic input on site selection, activation timelines, and enrollment risk mitigation.
• Serve as the escalation point for complex investigator and site relationship issues, partnering with Clinical Operations, Clinical Development, and Medical Affairs leadership to resolve challenges.
• Consolidate and communicate team-level field intelligence, enrollment trends, and performance metrics to senior leadership in a structured, actionable manner.
• Partner with cross-functional leaders in Clinical Development, Medical Affairs, and HR to ensure team alignment, appropriate resourcing, and consistent application of company policies.
• Support the development of team training, onboarding, and engagement playbooks for Clinical Engagement Leads in collaboration with Clinical Operations and Medical Affairs.
• Oversee team contributions to investigator-initiated study (IIS) identification and evaluation, ensuring scientifically relevant concepts are flagged, reviewed, and tracked in coordination with Medical Affairs.
• Oversee data quality and compliance of investigator interactions, site assessments, and clinical engagement activities recorded by the team in the CRM system, adhering to company policies and GCP standards.
• Perform other duties and responsibilities as assigned.

Qualifications

• Bachelor’s degree in a scientific or related discipline; advanced degree (MS or MPH) in a relevant clinical, biomedical, or pharmaceutical sciences discipline required.
• 10+ years of experience in clinical operations, clinical development, clinical research, or a field-based clinical engagement role within the pharmaceutical or biotech industry.
• 3+ years of direct people management experience, including leading, coaching, and developing field-based or matrixed teams.
• Demonstrated experience managing investigator relationships and supporting clinical trial site activation and enrollment.
• Experience collaborating with CROs, investigative sites, field medical teams, and HR/talent partners, including MSL partnerships.
• Strong scientific and clinical knowledge of immunology and inflammation, including disease biology, standard of care, clinical trial design, and the competitive clinical research landscape.
• Expertise in clinical trial site management and investigator engagement strategy, including site feasibility assessment, investigator identification, site initiation support, and enrollment optimization.
• Familiarity with clinical operations tools such as CTMS, CRM platforms (e.g., Veeva), and site management systems; experience overseeing team documentation of field activities to GCP and compliance standards.
• Proven ability to manage and develop a team of field-based professionals independently, prioritize team objectives strategically, and operate with minimal supervision across a broad geography.
• Coaching-oriented leadership style that builds genuine, long-term relationships with team members based on trust, accountability, and commitment to professional growth.
• Proactive performance management skills, translating team and field observations into actionable insights to improve program strategy, site selection, and enrollment performance.
• Exceptional interpersonal and communication skills, with the ability to engage team members in substantive performance and development conversations and discuss Beeline’s pipeline, protocol design, and I&I disease areas with investigators.
• Clear and structured internal communication, providing concise, actionable updates on team performance and field intelligence to senior leadership.
• Credible external ambassador, representing Beeline’s science and organizational values at investigator meetings, scientific conferences, and site visits with professionalism and enthusiasm.
• Ability to navigate complex stakeholder environments and communicate effectively with team members, academic physicians, research coordinators, site administrators, and IRB contacts.
• Willingness to travel 50%+ of the time, including occasional overnight stays, and work evenings/weekends for physician or patient events (in-person or virtual).
• Ability to manage a multi-state territory with a diverse customer base, depending on geography.

Pay

The expected salary range for this position is $199,750 - $258,000 USD, varying by location. Actual pay will be determined based on experience, qualifications, and other job-related factors. A discretionary annual bonus and long-term incentive award (e.g., equity) may be available based on individual and company performance.

Benefits

Beeline Medicines offers a comprehensive benefits package tailored to the country and region of hire, including:

• Competitive health and wellness coverage (structure and premiums vary by location).
• Paid time off, public holidays, and additional leave entitlements in accordance with local requirements.
• Flexible work arrangements/hybrid schedules where applicable.

Benefits vary by location and are subject to eligibility requirements, local regulations, and plan terms. Specific details will be provided during the offer process.