Clinical Engagement Regional Associate Director (Americas)

Beeline Medicines is a clinical-stage biotechnology company focused on developing and delivering category-leading precision therapies to transform the lives of people living with autoimmune and inflammatory diseases. With a portfolio of potential best-in-class and first-in-disease therapeutic candidates, Beeline is advancing medicines designed to provide durable, life-changing impact. Led by an established executive team and backed by world-class life science investors, the company brings scientific rigor and operational excellence to realize a world where people with immune-mediated diseases can live life fully.

About the role

The Clinical Engagement Regional Associate Director is a field-based, senior-level, people-management role responsible for leading a team of Clinical Engagement Leads (CELs) who build and manage investigator and site relationships across the organization’s clinical trial portfolio. This role serves as the central global people manager for the field-based clinical engagement function in assigned region(s), combining people leadership with deep knowledge of immunology and inflammation (I&I) therapeutic areas and clinical trial operations. The position acts as the escalation point for complex investigator and site issues and as the primary conduit of field intelligence and team performance to senior Clinical Development and Medical Affairs leadership.

This is a highly visible, field-based role requiring the ability to build and lead a high-performing team independently across a broad assigned geography. Regular travel within the designated territory is required, with additional travel possible for company meetings, training, or other business needs. The geographic territory (North America, Central America, & South America) is subject to change based on business priorities.

Responsibilities

• Provide day-to-day people leadership for a team of Clinical Engagement Leads, including coaching, performance management, goal-setting, and career development to build and sustain a high-performing field-based engagement team.
• Support site engagement strategy and priorities for the assigned region/country by translating clinical program goals into team-level objectives for investigator identification, site feasibility, activation, and enrollment performance.
• Recruit, onboard, and develop Clinical Engagement Lead talent in partnership with HR and Clinical Operations leadership on hiring decisions, territory/portfolio assignments, and skills development.
• Review and approve site engagement plans and feasibility recommendations, providing strategic input on site selection, activation timelines, and enrollment risk mitigation.
• Serve as the escalation point for complex investigator and site relationship issues, partnering with Clinical Operations, Clinical Development, and Medical Affairs leadership to resolve challenges.
• Consolidate and communicate team-level field intelligence, enrollment trends, and performance metrics to senior leadership in a structured, actionable manner.
• Partner with cross-functional leaders in Clinical Development, Medical Affairs, and HR to ensure team alignment, appropriate resourcing, and consistent application of company policies.
• Support the development of team training, onboarding, and engagement playbooks for Clinical Engagement Leads in collaboration with Clinical Operations and Medical Affairs.
• Oversee team contributions to investigator-initiated study (IIS) identification and evaluation, ensuring scientifically relevant concepts are flagged, reviewed, and tracked with Medical Affairs.
• Oversee data quality and compliance of investigator interactions, site assessments, and clinical engagement activities recorded in the CRM system, adhering to company policies and GCP standards.
• Perform other duties and responsibilities as assigned.

Requirements

• Bachelor’s degree in a scientific or related discipline; advanced degree (MS or MPH) in a relevant clinical, biomedical, or pharmaceutical sciences discipline required.
• 10+ years of experience in clinical operations, clinical development, clinical research, or a field-based clinical engagement role within the pharmaceutical or biotech industry.
• 3+ years of direct people management experience, with a track record of leading, coaching, and developing field-based or matrixed teams.
• Demonstrated experience managing investigator relationships and supporting clinical trial site activation and enrollment.
• Experience collaborating with CROs, investigative sites, field medical teams, and HR/talent partners, including MSL partnerships.
• Strong scientific and clinical knowledge of immunology and inflammation, including disease biology, standard of care, clinical trial design, and the competitive landscape.
• Expertise in clinical trial site management and investigator engagement strategy, including site feasibility assessment, investigator identification, site initiation support, and enrollment optimization.
• Familiarity with clinical operations tools such as CTMS, CRM platforms (e.g., Veeva), and site management systems; experience overseeing team documentation to GCP and compliance standards.

Skills

• Experienced people leader who manages and develops a team of field-based professionals independently, prioritizes objectives strategically, and operates with minimal supervision across a broad geography.
• Coaching-oriented leader who builds genuine, long-term relationships with team members based on trust, accountability, and commitment to professional growth and research excellence.
• Proactive performance manager who translates team and field observations into actionable insights to improve program strategy, site selection, and enrollment performance.
• Exceptional interpersonal and communication skills, with the ability to engage team members in substantive performance and development conversations and discuss Beeline’s pipeline, protocol design, and I&I disease areas with investigators.
• Clear and structured internal communicator who provides concise, actionable updates to leadership through regular written and verbal reporting.
• Credible external ambassador who represents Beeline’s science and values at investigator meetings, scientific conferences, and site visits with professionalism and enthusiasm.
• Skilled at navigating complex stakeholder environments, communicating effectively with team members, academic physicians, research coordinators, site administrators, and IRB contacts.

Schedule

• Position requires ability to travel 50%+ of the time, including occasional overnight stays driven by business need.
• Must be able to work evenings and weekends as needed for physician or patient events (both in-person and virtual).
• Depending on geography, must have the ability to manage a multi-state territory with a diverse customer base.

Pay

The expected salary range for this position varies by location and will be communicated based on the country or region of hire. Actual pay is determined by experience, qualifications, location, and other job-related factors permitted by local law. The salary range for this role is $199,750 - $258,000 USD. A discretionary annual bonus and long-term incentive award (e.g., equity) may be available based on individual and company performance.

Benefits

We offer a comprehensive benefits package tailored to the country and region of hire, in compliance with local laws and practices. Benefits may include:

• Competitive health and wellness coverage (structure and premiums vary by country).
• Paid time off, public holidays, and additional leave entitlements in accordance with local requirements.
• Flexible work arrangements/hybrid schedule.

Benefits vary by location and are subject to eligibility requirements, local regulations, and plan terms. Specific details applicable to your country or region will be provided during the offer process.