Clinical Biomarker Lead- Oncology Translational Medicine

About the Role

At GSK, we aim to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology. We foster a culture ambitious for patients, accountable for impact, and committed to doing the right thing.

We are seeking a Clinical Biomarker Lead in Oncology Translational Medicine to join our team in Collegeville, Pennsylvania. This role involves leading the development and implementation of biomarker strategies to support clinical development across GSK's portfolio. You will work with external partners, design and manage collaborative projects, and contribute to the advancement of novel biomarkers for clinical trials.

Responsibilities

• Work with external industry and academic partners to evaluate, validate, and establish key biomarker capabilities.
• Design, implement, and manage collaborative projects to develop biomarker capabilities aligned with GSK clinical trials.
• Identify and integrate cutting-edge advances in science and technology into biomarker strategies.
• Provide input to clinical biomarker teams on novel technologies to enable clinical development of candidate drugs.
• Manage effective working relationships with cross-functional teams, including clinical biomarker leads, medical affairs, oncology tumor teams, and portfolio management.
• Coordinate and manage biomarker projects with internal and external stakeholders.
• Contribute to the quality of biomarker reports, summaries, data reviews, and interpretations.
• Present key findings at internal and external scientific forums and lead the preparation of scientific manuscripts.

Qualifications

• Ph.D. with 3+ years or M.Sc. with 7+ years of drug development experience in the pharmaceutical industry, preferably in oncology biomarker development.
• Experience with biomarker assays, technologies, platforms, and providers.
• Experience implementing biomarker platforms such as flow cytometry, molecular diagnostics (NGS, FISH, PCR), and IHC/IF for oncology clinical trials.
• Experience designing and executing translational biomarker strategies in oncology clinical trials, including assay development, validation, and clinical deployment.
• Experience conducting biomarker analyses on various clinical sample types and delivering biomarker data packages to inform clinical and regulatory strategies.
• Experience coordinating and managing deliverables, timelines, contracts, and budgets with internal and external partners.
• Experience working to GCP/GLP principles.
• Ability to manage multiple priorities and deliver projects within established timelines in a fast-paced environment.

Preferred Skills

• Strong interpersonal skills and ability to thrive in a matrix environment.
• Dependable and trustworthy, with a willingness to take ownership and responsibility.
• Experience with high-dimensional dataset analysis.
• Strong communication, organizational, matrix project-management, and presentation skills.
• Experience with digital pathology, AI/ML-enabled biomarker analyses, and external scientific partnerships.

Pay

For candidates based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges from $150,975 to $251,625. The salary range considers factors such as work location, skills, experience, and market rates. This position also offers an annual bonus and eligibility to participate in our share-based long-term incentive program.

Benefits

• Health care and other insurance benefits (for employee and family)
• Retirement benefits
• Paid holidays, vacation, and caregiver/parental and medical leave

For more details, visit GSK US Benefits Summary.

Location

Collegeville, Pennsylvania, United States (on-site)