Clinical Biomarker Lead- Oncology Translational Medicine

About the role

This role will temporarily be based at Stevenage. However, the Company plans to relocate its offices to either Cambridge, UK or Ware. The location of this role will subsequently change to either Cambridge, UK or Ware in accordance with timelines set by the Company.

Responsibilities

• Work with key external industry and/or academic partners to evaluate, validate and establish key biomarker capabilities and/or generate key biomarker data to support biomarker strategies for clinical trial implementation at GSK.
• Design, implement and manage collaborative projects that aid in developing biomarker capabilities that are of strategic importance to OTM and in alignment with GSK clinical trials.
• Identify, develop and implement cutting edge advances in science and technology into biomarker strategies to guide indication selection, patient enrichment, and combination strategies.
• Provide input to clinical biomarker teams on novel technologies that will enable clinical development of GSK candidate drugs.
• Manage effective working relationships with clinical biomarker leads, medical affairs, oncology tumor teams, portfolio management, competitive intelligence, clinical development and OTM management.
• Cook up and manage biomarker projects with cross-functional internal stakeholders and external partners.
• Contribute to and ensure the quality of OTM biomarker reports, summaries, data reviews and interpretations as applicable.
• Present key data/findings/accomplishments at internal as well as external scientific forums, lead the preparation and publication of scientific manuscripts as needed.

Requirements

• Ph.D. or equivalent with 3+ years of drug development experience in pharmaceutical industry, preferably in oncology biomarker development.
• Experience with biomarker assays, technologies, platforms and providers.
• Experience of implementation of a range of biomarker platforms including flow cytometry, molecular diagnostics (NGS, FISH, PCR), and/or IHC/IF for Oncology clinical trials.
• Experience designing and executing translational biomarker strategies in oncology clinical trials, including assay development, validation, sample testing plans and clinical deployment.
• Experience conducting biomarker analyses on various clinical sample types and delivering biomarker data packages at pace to inform clinical development and regulatory strategies working collaboratively as part of cross-functional matrix teams.
• Experience coordinating and managing key deliverables, timelines, contracts and budgets with internal and external partners.
• Experience working to GCP/GLP principles.
• Experience managing multiple priorities and delivering projects within established timelines in a fast-paced environment.

Qualifications

• Strong interpersonal skills and ability to thrive in a matrix environment.
• Dependable and trustworthy, willing to take ownership and responsibility.
• Experience with high-dimensional dataset analysis.
• Strong communication, organizational, matrix project-management, and presentation skills.
• Experience with digital pathology, AI/ML-enabled biomarker analyses, and external scientific partnerships.

Skills

• Agile Thinking
• Clinical Development
• Clinical Trial Designs
• Decision Making
• Fostering Collaboration
• Influencing Without Authority
• Leadership
• Matrix Leadership
• Mentorship
• People Management
• Project Management
• Risk Management
• Strategic Thinking
• Teamwork
• Time Management

Benefits

The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role.

Pay

The annual base salary for new hires in this position ranges $150,975 to $251,625.

Schedule

The schedule for this role is not specified.