Chief Financial Officer at The END Fund

The END Fund is the world's leading collaborative philanthropic investment vehicle dedicated to controlling and eliminating neglected tropical diseases (NTDs).

About The Organization

The END Fund's vision is to ensure people can live healthy and prosperous lives free of the risk of Neglected Tropical Diseases (NTDs). NTDs are parasitic and bacterial infectious diseases – including intestinal worms, river blindness, trachoma, schistosomiasis, and lymphatic filariasis – that affect over 1.7 billion people globally. Since its founding in 2012 through 2025, with its partners, the END Fund has provided over 1.86 billion treatments for NTDs worth more than $3 billion.

To drive impact and achieve its vision, the END Fund focuses on:

• Mobilizing and investing resources for maximum impact
• Advocating for innovative, integrated, and cost-effective NTD programs
• Facilitating philanthropic and private sector engagement to end these diseases

By engaging a community of philanthropists and taking a systems approach, the END Fund works in collaboration with governments, local and international NGOs, pharmaceutical companies, and academic partners on the global campaign to control and eliminate the most prevalent NTDs by 2030. The END Fund operates globally in 30 countries, with a primary emphasis in Africa.

About The Role

The END Fund is seeking a Chief Financial Officer (CFO) to lead the organization's global finance function, overseeing financial planning, accounting, grants administration, audits, payroll, and compliance across the US, UK, and Kenya. Reporting to the Interim Chief Executive Officer (Interim CEO), the CFO will hold overall accountability for all finance functions and will be ultimately responsible for the organization's financial health and integrity.

This role calls for a strategic, mission-driven finance leader with deep nonprofit expertise, strong cost management skills, a sophisticated understanding of managing complex finances across multiple entities, and the ability to translate complex financial information into clear insights for the CEO, Board, and cross-functional teams. The CFO will strengthen financial systems, drive efficiency, promote data-driven decision making, and serve as a trusted advisor, partnering with leadership to support growth, maximize impact, and advance the END Fund's mission to eliminate NTDs within this decade.

Working closely with the Interim CEO, leadership colleagues, and Board of Directors during a time of transition, the CFO will provide sound information, advice, and thought partnership on organizational strategies and plans to ensure the END Fund can deliver the greatest impact. This includes ensuring robust financial controls and due diligence processes to offer assurance to funders and balance risk with the needs of partners.

The ideal candidate is a qualified accountant and strategic, mission-driven finance leader with deep nonprofit expertise and exceptional strategic and technical finance skills. They will have experience in forensic accounting and analysis, including knowledge of UK/US accounting principles and a proven track record in effective management of operational costs. Experience within an international nonprofit environment and managing program-restricted funding streams and compliance needs is strongly preferred.

The CFO will also be a highly effective communicator, demonstrating fluency and comfort presenting complex financial information to a wide variety of audiences, and influencing senior stakeholder groups including END Fund senior leadership, Board, and donors. The CFO must attract, develop, and motivate a high-performing and diverse finance team while empowering them to excel. Above all, the ideal candidate will demonstrate a strong commitment to the END Fund's vision, mission, values, and goals.

Responsibilities

Strategic Leadership

• Provide strategic oversight and direction for the organization's financial resources, partnering with the Interim CEO, COO, Board of Directors, and senior staff to develop short- and long-term finance and administration strategies.
• Oversee all fiscal and fiduciary responsibilities, ensuring strong financial stewardship and compliance across all legal entities (US, UK, and Kenya); ensure the overall health and success of a complex financial structure spanning multiple legal entities, global accounting practices, restricted and unrestricted funding, and other layers of complexity.
• Serve as a trusted advisor on financial decision-making, offering insight into organizational growth, operational priorities, and strategic opportunities.
• Support special projects led by the COO and CEO that advance organizational growth and impact.
• Provide clear, strategic direction and leadership across the finance team, fostering cohesion among a diverse team of professionals and cultivating a culture of excellence, learning, and accountability.
• Manage all employees of the department, including hiring, performance, and talent development.
• Partner with VPs and cross-functional teams to break down silos, align departmental spending with strategy, and ensure transparent understanding of financial implications across the organization.
• Serve as an active member of the leadership team, maintaining a comprehensive understanding of END Fund's programs and operations to guide financial strategies and decisions in alignment with budgetary and operational priorities.
• Collaborate with other relevant departments to ensure effective and timely communication with donors and implementing partners regarding funding opportunities, including grant management and fundraising.
• Lead organization-wide process improvement initiatives.

Financial Management & Reporting

• Ensure the preparation of statutory accounts and audits of all END Fund entities as required, including any other statutory reporting (e.g., annual corporation tax return to HMRC, VAT returns, submission of the 990 to the IRS) and compliance with all legal, tax, and regulatory requirements across the US, UK, and Kenya. Ensure all audits receive unqualified opinions.
• Lead the end-to-end financial operations, including accounts payable, accounts receivable, payroll, general ledger, fixed assets, and grants management.
• Oversee the development and implementation of policies and procedures to provide sufficient internal controls and protect organizational assets.
• Develop and submit an annual budget, ensuring that organizational activities are managed within parameters with accurate reporting on progress and challenges.
• Maintain a 5-year financial outlook and robust cash flow projections for the organization and oversee the ongoing monitoring of the budget and financial position.
• Build in strong forecasting systems that proactively update the Leadership Team on the organization's cash flow position, monitoring liquidity to ensure the organization can meet short-term obligations and managing the capital structure—balancing debt, equity, and internal financing to maximize performance.
• Ensure the production of timely and accurate management financial information for senior leadership, Finance, Audit and Risk Committee, Board, internal budget holders, and donors, translating complex financial data into actionable insights.
• Actively engage with the Board on finance and administrative matters.
• Manage due diligence, contract compliance, and reporting requirements for a range of donor types, including ensuring effective utilization of restricted funding sources.
• Ensure appropriate systems and processes are in place to manage financial aspects of grants to partners.
• Provide expert financial analysis and reporting to leadership, the Board, and cross-functional teams, translating complex financial data into actionable insights.
• Oversee the preparation of statutory financial statements, annual audits, and compliance with all legal, tax, and regulatory requirements across the US, UK, and Kenya.
• Develop and maintain robust cash flow projections and multi-year forecasting systems to support informed decision-making and ensure operational sustainability.
• Oversee treasury management, including managing currency needs.
• Maintain banking, auditor, investment manager, and other key supplier relationships.
• Implement rigorous segregation of duties and approval thresholds to ensure no single individual has total control over financial transactions.

Process Optimization & Cost Management

• Identify opportunities to improve financial systems, processes, and workflows to maximize efficiency, accuracy, and organizational impact.
• Implement strong internal controls, including segregation of duties and approval thresholds, to safeguard organizational resources.
• Optimize operational and vendor management practices to reduce costs and enhance financial performance.
• Partner with VPs and cross-functional teams to break down silos, align departmental spending with strategy, and ensure transparent understanding of financial implications across the organization.
• Lead change management efforts to support the team's successful adoption of new systems, processes, and/or technologies as needed to achieve increased efficiencies and strategic financial goals.
• Drive the organization's financial and operational sustainability, ensuring robust systems and processes across the organization that are fit for purpose, responsive, and compliant.
• Support the Finance team, in collaboration with Human Resources, to ensure that payroll processes and salary payments are managed professionally and in line with legislation in the country of operation.

Who You'll Work With

You will report to the Interim Chief Executive Officer. You will supervise a team of 5. You will serve on the Senior Leadership Team and frequently collaborate with cross-functional leaders across the Operations, Programs, Communications, and Fundraising teams.

Requirements

• Qualified accountant (CPA, ACA, CIMA, ACCA, or equivalent) with extensive expert-level experience, including financial planning, administration, accounting, and team management at an executive level.
• Experience leading finance in a nonprofit organization is required; global experience strongly preferred.
• Experience overseeing finance for organizations with annual budgets of $50M or more.
• Excellent technical financial skills, including knowledge of UK and/or US accounting and sophisticated usage of Microsoft Excel.
• Deep understanding of nonprofit structures, accounting operations, grants management, and disbursements, with working knowledge of GAAP and 501(c)(3) regulations. Specific experience managing finances, donor reporting, and compliance for an organization with complex restricted funding streams.
• Strong knowledge of data analysis, forecasting & financial modeling, investments, financial reporting, budgeting, audit, tax, strategic planning, internal controls, and risk management.
• Strong communication skills, both verbal and written, with a facility for preparing and clearly presenting financial information to non-financial and financial audiences.
• Experience negotiating and influencing at a strategic level and building strong relationships with stakeholders.