Biologist II

Duties And Responsibilities

• Validate and perform independently cell-based and membrane-based assays for novel therapeutics.
• Perform cell culture and various in vitro biochemical assays.
• Daily support in maintaining and generating cell lines including transfected and immortalized mammalian cells for assays.
• Calculate seeding densities and maintain frozen stocks in liquid nitrogen.
• Apply and program state of the art automation to enable compound testing in microtiter plate assay format.
• Experience with multidrop reagent dispenser, Tecan liquid handler, and Echo acoustic instrumentation.
• Develop and perform assays in receptor pharmacology including target binding, functional cellular readouts such as cAMP production, phosphorylation, calcium levels, and beta-arrestin recruitment, and other biomarkers that would include standard molecular and cellular biology techniques.
• Critically evaluate data and quality metrics independently.
• Prepare result summaries in written and oral formats.
• Track storage and log of preclinical exploratory research samples.
• Identify published scientific evidence to perform and refine early assay development.
• Accurate record keeping and reporting of data adhering to client note booking policy.
• Good communication skills, organization, and multitasking of job duties.
• Ability to be proactive, flexible, and capable of independent troubleshooting and problem solving.
• Maintain inventory of laboratory consumables and reagents while communicating clearly to lab managers.
• Report on project status weekly and adhere to deadlines established by management teams.
• Follow guidelines set forth with clients and in the company Safety Manual / Chemical Hygiene Plan.
• Other duties as defined by manager, department needs, and workload.

Skills & Proficiencies

• Data analysis – familiarity with Excel, GraphPad Prism, Teams, Sharepoint, PowerPoint, GeneData Screener.
• Experience with cellular and biochemical techniques including cell culture.
• Pipetting skills and aseptic technique.
• Understanding of basic scientific terminology and ability to communicate it to others.
• Ability to multitask and be organized.
• Professional, clear, and concise communication required in written and verbal formats.
• Possess strong organizational skills with ability to quickly assess project status and communicate effectively.
• Work in team-oriented environment within cross-functional project teams.
• Strong interpersonal skills such as communication, being approachable, showing initiative, adaptability, projecting positive attitude and ability to inspire others.
• Knowledge of scientific research principles, practices and protocols.
• Champion company values including team engagement.

Education And Experience

• Degree requirement: Bachelor's Degree in Biology or closely related field.
• Minimum of one (1) year of experience in the laboratory performing experiments and evaluating data.
• An equivalent combination of education and experience may be accepted in lieu of above.