Biologist I/II

Location: Worcester, MA (100 Research Dr. – Onsite)

Pay Rate: Biologist I: $33/hr and Biologist II: $35-41/hr
Duration: 12 Months (High Possibility of Extension)

About the role

Seeking a Biologist I/II to support biologics drug discovery and multispecific antibody engineering programs. This role focuses on protein expression, purification, remediation, and analytical characterization of complex biologics to support discovery research activities.

Responsibilities

• Express, purify, and remediate multispecific biologics, antibodies, and antibody fragments
• Perform protein purification using chromatography techniques and AKTA platforms
• Characterize proteins using SEC, LC-MS, DSF, SDS-PAGE, and endotoxin assays
• Perform analytical testing and protein quality assessments to support biologics discovery programs
• Execute purification workflows including SEC, HIC, and IEX chromatography
• Support antibody engineering, design, and optimization activities
• Utilize sequence analysis software to support biologics development workflows
• Manage sample preparation, aliquoting, tracking, and cross-functional sample transfers
• Support automated biologics workflows using laboratory automation platforms
• Maintain electronic laboratory records and generate experimental reports
• Coordinate multiple research requests to ensure timely delivery of biologic materials

Requirements

• Bachelor’s or Master’s degree in Biology, Biochemistry, Biotechnology, Molecular Biology, or related field
• Biologist I: 1-2 years of relevant pharmaceutical or biotechnology experience with BS degree
• Biologist II: 3+ years of relevant biologics research experience or equivalent technical expertise

Skills

Required

• Protein expression and purification
• Antibody and antibody fragment purification
• Multispecific biologics characterization
• AKTA chromatography systems
• SEC (Size Exclusion Chromatography)
• HIC (Hydrophobic Interaction Chromatography)
• IEX (Ion Exchange Chromatography)
• LC-MS protein characterization
• DSF (Differential Scanning Fluorimetry)
• SDS-PAGE analysis
• Endotoxin testing
• Protein remediation workflows
• Sequence analysis tools (Vector NTI, Geneious, Genedata)
• Electronic laboratory notebooks
• MS Excel, PowerPoint, and Word

Preferred

• Multispecific antibody development
• Antibody engineering and optimization
• Biologics discovery experience
• Laboratory automation platforms (Hamilton, Tecan, AssayMap, KingFisher)
• Automated protein purification workflows
• Complex biologics characterization
• Pharmaceutical industry research experience