Bioinformaticist

Responsibilities

• Working with exome sequencing, methylation arrays, methylation sequencing, ATAC-seq, miRNA-seq, RNA-seq, and ChIP-Seq bioinformatic workflows.
• Working with high throughput scRNA-Seq, scATAC-Seq analysis using existing single cell analysis software like Seurat and established single cell pipelines.
• Using methods like principal component analysis, spectral decomposition, t-SNE, UMAP for data visualization and clustering techniques like k-means clustering, agglomerative hierarchical clustering, graph partitioning etc. for cell type annotations.
• Regulatory network analysis and genetic annotation of data.
• Participating in collaborative projects with other leading academic research and industry collaborators on computational analysis of high-dimensional, cell and molecular profiling data to advance precision microbiome efforts.
• Perform analyses in a transparent manner and to clearly communicate analysis results and methods with collaborating researchers who may or not have computational backgrounds.
• Guiding and training other staff, as well as performing certain administrative functions, as necessary, to ensure smooth functioning of experiments and timely distribution of program deliverables.

Qualifications

• Ph.D. OR a M.S. with at least 2 years of relevant industry experience.
• Degree must be in bioinformatics, biology, genetics, computer science, mathematics, or a related scientific discipline.
• Expertise in analysis, interpretation and bioinformatics research on large multivariate molecular profiling datasets to include methylation, ATACseq, transcriptomics, and single cell multiome.
• Experience developing and integrating data and tools to distill knowledge from large datasets.
• Excellence in relevant programming languages (ideally Python and/or R).
• A track record demonstrating scientific creativity, collaboration, and independence.
• Must be a US citizen with the ability to obtain and maintain required government security clearances as a condition of employment.
• The ability to work in a team environment.
• Excellent written and oral communication skills.