Jobs · Analyst · California

Associate Scientist – Protein Sciences

Kite Pharma · San Francisco Bay Area · 1 wk ago
Analyst$110k–$142k/yrFull-time

About the role

We are seeking a highly motivated Associate Scientist to support our Protein Sciences team. This individual will contribute as a hands-on laboratory scientist, executing protein production, purification, and analytical workflows that support multiple CAR-T and cell therapy programs.

Responsibilities

  • Execute recombinant protein expression and purification workflows across multiple expression systems (e.g., mammalian cell culture, transient transfections)
  • Perform protein purification using AKTA chromatography systems (affinity, SEC, ion exchange)
  • Maintain cell cultures and support transfection workflows
  • Analytical Characterization
    • Perform biochemical and biophysical characterization of proteins and antibodies, including:
      • SDS-PAGE and Western blot
      • UPLC/HPLC-based purity assessment
      • Binding assays (e.g., Octet/BLI)
  • Document and summarize experimental data clearly to support team decision-making
  • Protein Modification & Assay Support
    • Perform antibody and protein conjugation workflows with appropriate analytical follow-up
    • Prepare reagents and materials to support downstream functional assays (e.g., flow cytometry or cell-based assays in collaboration with Cell Biology partners)
  • Lab Operations & Execution
    • Maintain organized lab practices, including reagents, consumables, and shared equipment
    • Accurately document experimental documentation in electronic lab notebooks and LIMS
    • Follow established SOPs and contribute to maintaining reproducibility and data quality standards
  • Collaboration
    • Work closely with cross-functional partners to execute experiments aligned with defined protocols and timelines
    • Communicate experimental progress and results effectively to project teams

Qualifications

  • Advanced scientific degree (MD, PharmD, PhD) OR Master’s degree with 4+ years of relevant scientific experience OR Bachelor’s degree with 6+ years of relevant scientific experience
  • Preferred Qualifications: Bachelor’s or Master’s degree in Biochemistry, Molecular Biology, Protein Science, or related field 2–4+ years of relevant hands-on laboratory experience in academic or industry settings
  • Experience with recombinant protein expression and purification workflows
  • Hands-on experience with AKTA systems and chromatography methods
  • Familiarity with protein characterization techniques (SDS-PAGE, HPLC, BLI/Octet, etc.)
  • Experience with mammalian cell culture and transfections
  • Strong attention to detail and commitment to high-quality data generation and documentation
  • Ability to follow protocols, troubleshoot at the experiment level, and work effectively in a fast-paced lab environment

Pay

The salary range for this position is: $109,650.00 - $141,900.00. Kite considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary.

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