Associate Scientist II (Contract), Research
Vaxcyte · San Carlos, CA · 2 wk ago
OTHRContract
Essential Functions
- Execute the following AKTA FPLC chromatography techniques:
- Immobilized metal affinity chromatography (IMAC)
- Ion-exchange chromatography (IEX)
- Hydrophobic interaction chromatography (HIC)
- Size-exclusion chromatography (SEC)
- Hydroxyapatite (CHT / HA)
Requirements
- BS in Biochemistry, Molecular Biology or a relevant science considered, with minimum of 2 years of relevant industry experience or MS with minimum of 1 year of relevant industry experience.
- Experience with diverse protein targets, bacterial and eukaryotic recombinant proteins, small/large subunit vaccine antigens, fusion proteins, multimeric complexes, glycoproteins, and VLPs.
- The role requires demonstrated success with alternative capture/polishing methods and orthogonal cleaning strategies appropriate for potential vaccine antigens.
- PREFERRED: Experience with Cell-free protein synthesis system.
- Familiarity with automation or high throughput workflows such as (96-well plates) and UNICORN/AKTA software DoE integrations.
- Experience in process development.
- Strong interpersonal skills to collaborate well within the team and excellent written and verbal communication skills.