Associate Scientist I, Discovery Chemistry Operations

About the role

Arrowhead Pharmaceuticals is seeking an Associate Scientist to join the Discovery Chemistry Department. The successful candidate will primarily focus on oligonucleotide conjugation, purification, and characterization. They will be joining a team of highly motivated and experienced scientists and will contribute to the success of Arrowhead programs.

Responsibilities

• Conjugate compounds of interest to oligonucleotides through established protocols
• Optimize methods of conjugation to a diverse set of biomolecules and small molecules
• Troubleshoot reaction conditions to improve yields and purity
• Document lab work through an electronic lab notebook
• Track progress against project timelines, generate regular status updates, and communicate progress and issues to management
• Perform tasks across multiple projects
• Manage time effectively to meet deadlines
• Adhere to safe laboratory practices

Requirements

• Bachelor's Degree in Chemistry or Biochemistry with excellent understanding of organic and analytical chemistry
• 0-2 years of experience working in a chemistry laboratory
• Experience with a wide range of analytical techniques, especially HPLC

Skills

• Experience with large-molecule synthetic targets (especially oligonucleotides), in an academic or industry setting
• Previous experience working in a synthetic chemistry lab

Pay

Wisconsin pay range: $60,000 USD - $68,000 USD

Benefits

Arrowhead provides competitive salaries and an excellent benefit package.