Associate Researcher-Cell Developmental & Regenerative Biology (Blanchard Lab)
About the role
The Blanchard Laboratory at the Icahn School of Medicine at Mount Sinai is seeking passionate and highly motivated individuals to join our team working on a funded NASA-supported research program investigating how spaceflight and environmental stressors influence the human brain and neurodegenerative disease risk. Researchers will work closely with members of the laboratory to engineer iPSC-derived vascular and multicellular 3D models of the human brain and apply these platforms to study mechanisms underlying Alzheimer’s disease and related neurodegenerative disorders. These models are also being adapted for spaceflight experiments on the International Space Station, providing a unique opportunity to participate in cutting-edge work at the intersection of stem cell biology, neuroscience, and space medicine.
Responsibilities
- Culturing and maintaining human iPSC lines and derived cell types
- Generating and maintaining 3D brain and vascular models
- Performing microscopy-based analysis and experimental assays
- Aiding in the design, execution, and analysis of experiments
- Preparing specialized culture media and reagents
- Maintaining inventories of stem cell reagents and laboratory supplies
- Managing cryopreserved cell line stocks stored in liquid nitrogen
- Supporting laboratory organization and experimental documentation
Qualifications
- Bachelor's degree in science or related field preferred, or combination of relevant research experience and education
- 0-2 years of research/laboratory experience
- Preferred requirements include:
- Recent graduate with demonstrated experience in any of the following fields: cell biology, molecular biology, biochemistry, neuroscience, and developmental/stem cell biology, bioengineering
- The ideal candidates will have experience in the following research areas: iPSC cell culture and differentiation; molecular and cell biology; CRISPR, bioengineering, confocal microscopy; calcium imaging and optogenetics; mouse models; computational biology, single cell/nuclei RNAseq.