Associate Principal Scientist, Immunology Discovery

About the role

The Discovery Immunology organization is developing and advancing innovative therapies for inflammatory and autoimmune diseases across Gastroenterology, Rheumatology and Dermatology, to address significant unmet medical needs. We are seeking an Associate Principal Scientist with strong background in Immunology and experience in drug discovery to join our Immunology Discovery team in San Diego, CA.

Responsibilities

• Define and drive drug discovery immunology project/program strategies and collaborate effectively with colleagues within Discovery Immunology and across other functional areas (i.e. Discovery Biologics, Quantitative Biosciences, Pharmacokinetics, Dynamics, Metabolism and Bioanalytics) to achieve organizational objectives
• Participate in and/or lead multiple cross-functional teams to advance therapeutic candidates from early discovery to clinic, ensuring successful and timely completion of project/program milestones
• Lead from the bench - independently designing, executing and interpreting complex in vitro and ex vivo studies aligned with program goals, while also leading and overseeing the experiments of others
• Identify, validate and implement new and innovative approaches (including novel technologies) to increase efficiency and productivity and drive program progression
• Share expertise with colleagues and provide mentorship to less experienced scientists to ensure a culture of scientific rigor, collaboration and continuous learning
• Integrate and interpret complex data and communicate science and strategy to stakeholders and management

Qualifications

• Education: Ph.D. (with 5+ years) in immunology, cell biology or related biomedical science and relevant drug discovery experience with demonstrated experience contributing to or leading discovery-stage programs or initiatives
• Required Experience And Skills:
  • Strong immunology background with extensive knowledge of immune-mediated diseases across Gastroenterology, Rheumatology or Dermatology, and related preclinical models
  • Broad experience in cell biology techniques (including culture of cell lines, immune cells and other primary cells, in vitro and ex vivo cell-based assays, multi-color flow cytometry), immunoassay platforms (e.g. ELISA, meso scale discovery) and molecular biology (e.g. RT-PCR)
  • Proficiency in data analysis using Excel, Prism (GraphPad), FlowJo
  • Strong problem-solving and critical thinking skills
  • Ability to work independently and operate effectively within cross-functional and matrixed teams
  • Ability to lead by influencing and mentoring others
  • Ability to communicate data and program strategies effectively to broad audiences
• Preferred Experience And Skills:
  • Experience leading cross-functional biologics or chemistry discovery programs for Gastroenterology, Dermatology, and/or Rheumatology, especially autoimmune or immune-mediated disorders, including in both large and small pharma contexts
  • Prior experience working with multiple therapeutic modalities (small molecule, peptide, biologic, etc.)

Requirements

• As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.
• We are committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities.
• Please click here if you need an accommodation during the application or hiring process.
• The salary range for this role is $142,400.00 - $224,100.00.
• This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting.
• An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.