Associate Director, Translational Research and Biomarkers

About the role

The Associate Director of Translational Research and Biomarkers is an integral member of the Translational Biomarkers team and plays a pivotal role in advancing drug candidates from preclinical research through clinical development. This position requires expertise in immunology and nephology, clinical translational research, and data analysis, visualization and interpretation.

Responsibilities

• Participate as a key member of cross-functional project teams supporting asset development programs with active biomarker initiatives.
• Collaborate effectively within a cross-functional, matrixed environment—including Research, Preclinical, Clinical, Bioanalytical, Genomics, Regulatory, and Project teams—to refine translational hypotheses and deliver high-quality, program-critical outputs on accelerated timelines.
• Contribute to the design and advancement of scientifically rigorous biomarker and clinical development strategies, including indication and patient population selection, TE/PD biomarker integration, and MoA hypothesis development.
• Contribute to the selection, outsourcing, and execution of biomarker assays in biological matrices, and manage external vendors to ensure quality and timeliness.
• Develop and implement biomarker analysis plans and support high-quality data generation for interim and final clinical analyses.
• Ensure compliance with global regulatory guidelines for biomarker data generation, reporting, and submissions, when applicable.
• Evaluate, recommend, and help defend the adoption of emerging technologies and innovative approaches to enable biomarker measurement in biological matrices for clinical trials.

Requirements

• PhD or MS with a minimum of 5 years of relevant experience in clinical research or clinical trial execution within immunology/nephrology.
• Demonstrated experience designing and executing biomarker and genomics research, with a proven ability to analyze, interpret, and translate data to support drug development and inform clinical trial design.
• Strong expertise across a broad range of biochemical, molecular, and cellular assay platforms, as well as bioinformatics approaches, including RNA-Seq, exome and whole genome sequencing, high-throughput proteomics, and multiplex flow cytometry.
• Working knowledge of digital biomarker applications and their integration into clinical development programs.
• Experience managing external vendors, including oversight of timelines, deliverables, contractual obligations, and regulatory compliance.
• Proven ability to manage and contribute to multiple programs at different stages of development, effectively prioritizing work in a fast-paced environment with evolving timelines.
• Demonstrated ability to translate insights from scientific literature into the design, execution, and interpretation of complex experiments and research strategies.
• Excellent verbal and written communication skills, with the ability to clearly present complex scientific concepts and data to diverse cross-functional audiences.

Qualifications

• Minimum $169,222.00 - Maximum $253,000.00, plus incentive opportunity.

Skills

• Expertise in immunology and nephology.
• Strong background in clinical translational research.
• Proficiency in data analysis, visualization, and interpretation.
• Experience with a variety of biochemical, molecular, and cellular assay platforms.
• Knowledge of digital biomarker applications.
• Ability to manage external vendors and oversee timelines, deliverables, and regulatory compliance.
• Strong communication and presentation skills.

Benefits

• Comprehensive medical, dental, vision, prescription drug coverage.
• Company provided basic life, accidental death & dismemberment, short-term and long-term disability insurance.
• Tuition reimbursement.
• Student loan assistance.
• A generous 401(k) match.
• Flexible time off.
• Paid holidays.
• Paid leave programs.

Pay

$169,222.00 - $253,000.00, plus incentive opportunity.

Schedule

Full-time.