Associate Director, Translational Medicine, Neuroscience

About the role

Translational Medicine at Bristol Myers Squibb facilitates the transition of drug candidates from early to late-stage clinical development, their approval and life cycle management. Early-stage activities determine dose-schedule and responsive patient populations based on deep understanding of drug mechanism of action and disease segments. Late-stage activities build upon early work, exploring mechanisms of response/non-response, rational drug combinations and product differentiation, and developing translational strategies to support registrations and life-cycle management.

Translational disease strategies in Alzheimer’s /Neurological Diseases are derived from long term investments in developing data and deep expertise in disease biology, neuroinflammation and patient segments to assist science driven strategies for the development of the neuroscience pipeline.

Responsibilities

• Develop and execute translational disease strategy in Alzheimer’s /Neurological disease areas with deep disease expertise
• Lead and oversee execution of disease strategy including patient selection strategies
• Serve as scientific expert in generating novel hypotheses for targetable biologies based on novel discoveries integrating disease work with literature and deep expertise in neuroscience
• Manage cross functional disease project teams with key interfaces in IT, bioinformatics, data science, statistics, external collaborators, contractors, other disease strategy leads and asset leads
• Maintain relationship with translational clinicians for identifying new opportunities and for gaining disease insight
• Identify needs, gaps and translational disease questions and apply knowledge across all assets in BMS portfolio in neuroscience area
• Lead small and large collaborations with academia and industry partners to identify biobanks, clinical trials and existing databases to collate multi-parameter genomic, immune and clinical datasets to mine for novel biomarkers of unmet need patients in conjunction with computational biologists, data scientists and statisticians
• Collaborate and guide bioinformatics partners on biological questions to deliver biomarkers and biological understanding from whole transcriptome, whole exome, and/or whole genome data, epigenetics, proteomics, immune profile and single cell data in order to support drug discovery and development in Alzheimer’s /Neurological Diseases
• Manage relationships with key internal stakeholders including regulatory, clinical and commercial and scientific communications and external collaborators to develop translational analysis plans and timelines, communicate analysis results
• Represent the Neurology Translational Medicine function at various internal meetings and provide domain knowledge and disease expertise to cross-functional teams
• Direct and support publications in high quality scientific, technical or medical journals

Qualifications & Experience

• PhD degree in a neuroscience-related field
• Minimum of 8 years post-PhD experience, with demonstrated scientific leadership in integrating, analyzing, and interpreting multimodal biological data in an academic and/or industry setting
• Strong background in neuroscience with focus on Alzheimer’s disease, human genetics/genomics, molecular and cellular biology
• Knowledge in immunology is a plus
• Ability to work in a fast-paced environment with rapidly changing and competing priorities and ambiguity
• Strong team player with the ability to work in cross-functional teams
• Excellent communication and collaboration skills
• Prior experience with clinical trials preferred but not essential
• Strong track record of high-quality scientific publications in relevant fields

We hire for skills and capabilities, not just credentials – if this role excites you, but doesn’t perfectly match your resume, we encourage you to apply anyway.

Compensation Overview

Brisbane - CA - US: $184,060 – $223,036

Cambridge Crossing: $184,060 – $223,036

Princeton - NJ - US: $160,060 – $193,949

San Diego - CA - US: $176,050 – $213,334

The starting pay range(s) listed above is for full-time employees (FTE). You may also be eligible for additional discretionary incentive cash and stock opportunities. We determine starting pay thoughtfully – carefully considering the nature of the role, required skills, work location, schedule and the knowledge and experience you bring. Final compensation is guided by pay equity principles and applicable employment laws. Compensation programs are reviewed on an ongoing basis and may be adjusted over time to reflect evolving market factors, and individual, team or Company performance.

Benefits

Subject to the terms and conditions of the applicable plans then in effect, you may be eligible to participate in our comprehensive benefit plans – including wellbeing support, retirement and financial protection benefits, and insurance offerings (medical, dental, vision, life and disability).

U.S.-based exempt employees are eligible for Flexible Time Off (FTO), which provides paid time off without a set accrual limit, subject to manager approval, along with 11 paid company holidays each year. Non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires (subject to manager approval), 11 paid company holidays, and 3 optional holidays. Depending on eligibility, employees may also have access to additional time-off benefits, including paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, caregiver, bereavement, or military needs.

Eligible employees also enjoy an annual Global Shutdown between Christmas Day and New Year's Day.