Jobs · Science

Associate Director, Specimen Management & Lab Start-Up, Remote

Merck · North Wales, PA · Yesterday
Science$142k–$224k/yrFull-time

About the role

The Associate Director, Specimen Management & Lab Start-Up is responsible for leading and overseeing laboratory study start-up and specimen management activities across a portfolio of clinical trials. This role ensures the successful planning, implementation, and execution of laboratory-related operational requirements to support study initiation, specimen collection, processing, shipment, tracking, reconciliation, and issue resolution.

Responsibilities

  • Lead laboratory and specimen management activities during study start-up for assigned clinical trials or programs.

  • Review study protocols to assess specimen collection, processing, storage, shipment, and testing requirements.

  • Oversee development and review of laboratory manuals, specimen collection guidelines, requisition forms, and related study documents.

  • Capture and coordinate central laboratory, specialty laboratory, and provider set-up activities to ensure operational readiness prior to site activation.

  • Partner with study teams to align laboratory timelines with broader study start-up milestones.

  • Identify study risks related to specimen handling or lab operations and implement mitigation plans.

  • Oversee end-to-end specimen lifecycle management processes, including: collection requirements, processing workflows, packaging and shipment, chain of custody, sample tracking, reconciliation, discrepancy management.

  • Ensure specimen operations are executed in accordance with protocol, our expectations, and internal standards.

  • Monitor sample-related metrics, quality issues, and trends to drive timely issue resolution and performance improvement.

  • Provide escalation support for specimen-related operational issues that may impact sites, laboratories, or study timelines.

  • Manage relationships with central laboratories, specialty laboratories, courier/logistics providers, and kit providers.

  • Support provider selection, feasibility assessments, scope review, and operational planning.

  • Oversee provider performance against service level agreements (SLAs), turnaround times, quality expectations, and study deliverables.

  • Facilitate provider governance meetings, performance reviews, and issue escalation/resolution.

  • Ensure external partners are aligned with protocol-specific sample handling requirements and study timelines.

  • Collaborate closely with Clinical Operations, Biomarker Managers, Pharmacokinetics, Data Management, Regional teams, Quality, and other internal stakeholders to support seamless study execution.

  • Act as the subject matter expert for specimen management and lab start-up processes during study planning and execution.

  • Provide recommendations on protocol feasibility and operational design related to specimen collection and laboratory workflows.

  • Communicate study risks, readiness status, and key specimen management updates to internal and external stakeholders.

  • Ensure specimen management and lab start-up activities comply with: Good Clinical Practice (GCP), Applicable GxP requirements, IATA/DOT shipping regulations, internal SOPs and quality standards.

  • Maintain inspection readiness for laboratory and specimen-related processes.

  • Support deviation investigations, root cause analysis, corrective and preventive actions (CAPA), and quality improvement initiatives.

  • Promote consistent documentation practices and operational compliance across studies and teams.

  • Provide day-to-day leadership, coaching, and guidance to specialists, senior specialists, and/or managers supporting specimen management and lab start-up activities.

  • Aid in workload planning, prioritization, and resource coordination across assigned studies or programs.

  • Contribute to staff development, training, onboarding, and performance feedback.

  • Foster a collaborative, accountable, and continuous-improvement-focused team culture.

  • Evaluate existing specimen management and start-up processes to identify opportunities for improvement, standardization, and scalability.

  • Support implementation of new technologies, tools, and workflows to improve specimen visibility, tracking, and operational efficiency.

  • Develop and report key performance indicators (KPIs) related to study start-up readiness, sample quality, reconciliation, and provider performance.

  • Lead or contribute to strategic initiatives to improve site experience, data quality, and operational execution.

Qualifications

  • Bachelor’s degree required.

  • Minimum of 5 years in laboratory, biopharmaceutical and/or the supplier industry.

  • Proven experience in specimen management and lab start-up.

  • Strong interpersonal skills including cross-functional teamwork, and written and oral communication skills, negotiation skills, exceptional analytical skills, multi-cultural skills, high energy level, and a bias toward action.

  • Solid understanding of clinical development and operations best practices.

  • Microsoft office skilled (e.g., excel and power point).

  • Biorepository system background preferred.

Preferred Qualifications

  • Previous biorepository and/or specimen management experience.

  • Previous clinical trial management experience.

  • Previous experience in the supplier industry.

  • Previous experience in project management.

  • Previous experience in risk management.

  • Previous experience in schedule management.

  • Previous experience in stakeholder communications.

  • Previous experience in test lab management.

Skills

  • Current Employees apply HERE

  • Current Contingent Workers apply HERE

  • US And Puerto Rico Residents Only

  • We are committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities.

  • Please click here if you need an accommodation during the application or hiring process.

  • Requirements

  • Equal Employment Opportunity Employer

  • Personal Rights Under the U.S. Equal Opportunity Employment laws

  • Salary Range

  • Requisition ID: R409417

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