Associate Director Quantitative Pharmacology

About the role

The Associate Director will lead model-informed drug development strategies supporting one or more therapeutic areas across modalities including antibodies, siRNA, and gene therapies. This role combines scientific depth with cross-functional leadership to inform dose selection, trial design, and regulatory strategy from early development through submission.

Responsibilities

• Drive model-informed development (MIDD) and pharmacometrics strategies in partnership with Clinical Pharmacology, Biostatistics, Clinical and Translational teams to support regulatory and clinical decision-making.
• Lead the QP evaluation of one or more assets, accountable for timely delivery of population PK/PD, exposureresponse, and translational modeling analyses.
• Represent QP at program and governance meetings, communicating quantitative insights clearly to non-modeling audiences.
• Contribute to regulatory interactions and author key components of regulatory documents related to QP (e.g., IB, briefing books, etc.).
• Mentor and develop junior scientists and foster a culture of scientific rigor and collaboration.
• Identify and implement process improvements, new modeling approaches, and innovative quantitative tools to enhance efficiency and impact.
• Ensure analyses and documentation are of the highest scientific quality and regulatory compliance.

Requirements

• PhD in Quantitative Pharmacology, Pharmacometrics, Engineering, or a related field with 6+ years of post-doctoral or industry experience; or MS with 9+ years of relevant experience.
• Demonstrated expertise in population PK/PD, exposureresponse, or mechanistic modeling (systems biology, or QSP) using tools such as NONMEM, Monolix, Simulx, MATLAB/Simbiology and R.
• Proven track record of delivering analyses supporting regulatory submissions and engaging directly with agencies (e.g., FDA, EMA, PMDA).
• Hands-on experience with a broad range of quantitative and computational tools and a strong publication record.
• Exceptional communication and interpersonal skills, with the ability to influence and partner effectively across technical and non-technical teams.

Qualifications

• Desired education: PhD in Quantitative Pharmacology, Pharmacometrics, Engineering, or a related field; or MS with 9+ years of relevant experience.
• Experience: 6+ years of post-doctoral or industry experience in Quantitative Pharmacology, Pharmacometrics, Engineering, or a related field; or 9+ years of relevant experience.
• Skills: Expertise in population PK/PD, exposureresponse, or mechanistic modeling (systems biology, or QSP); demonstrated experience with tools such as NONMEM, Monolix, Simulx, MATLAB/Simbiology and R; proven track record of delivering analyses supporting regulatory submissions and engaging directly with agencies; hands-on experience with a broad range of quantitative and computational tools; exceptional communication and interpersonal skills.

Skills

• Data-driven decision making
• Collaboration and leadership
• Clear communication
• Process improvement
• Innovative thinking

Benefits

Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits.

Pay

$176,100.00 - $287,300.00 annually

Schedule

Full time