Associate Director, Program Management

About the role

At Alnylam, development-stage programs are managed by Program Leadership Teams, led by a Program Leader and a Program Manager, responsible for harnessing cross-functional expertise to define the best scientific, clinical, and commercial strategies and plans for the success of the Program. The Associate Director, Program Management CNS partners with Program Leaders to drive program strategy and execution of assets in Alnylam’s CNS portfolio. This role provides a combination of drug development, stewardship, and program expertise to the Program Leadership Teams and has significant responsibility for developing, driving, operationalizing, and executing the program strategy. The candidate will also drive the identification and implementation of Program Management best practices within Alnylam.

This role reports to the Director, CNS Program Management and is hybrid, primarily located in Cambridge, MA.

Responsibilities

• Partner closely with Program Leader to shape and execute the Program strategy, goals, and plans, ensuring tight alignment with portfolio strategy.
• Lead development and drive execution of Program workplans, timelines, and integrated development plans with milestones, goals, key events, risks, assumptions, and scenarios.
• Drive coordination of cross-functional activities and promote effective communications (e.g., team meetings, program updates); integrate people involved within the program (e.g., clarity of responsibilities).
• Coordinate and co-lead critical, defined sub-teams for efficiency.
• Ensure clear, timely, and substantive updates on Program progress and issues to Senior Leadership in partnership with the Program Leader.
• Manage Program Team meetings, including leading discussions to drive decision-making, agenda creation, and meeting minutes; ensure ready access to these materials for Program Team members.
• Serve as a key point person for Program Team members and governance teams.
• Own key global program documents, e.g., integrated development plan, risk plan, and additional key status and timeline updates.
• Align with finance on all financial aspects of the Program, including liaising with collaboration partners, if applicable.
• Provide expertise on program management initiatives, including alignment of processes, tools, and technologies that aid in portfolio management across the organization.

Requirements

• Bachelor’s degree required; advanced degree in sciences or related field highly preferred.
• Minimum of 8+ years total experience in the pharmaceutical or biotechnology industry with in-depth knowledge of drug discovery, research, and development processes; strong preference for CNS development-stage experience.
• Direct drug development program management experience, with ability to work in research and preclinical programs.
• Strong leadership skills and ability to set team priorities and drive results within a matrixed, collaborative, and dynamic team environment.
• Excellent written and oral communication, including presentation and facilitation skills.
• Strong analytical and problem-solving skills; ability to combine attention to detail within a broader strategic context.
• Superior collaboration and negotiation skills, and high degree of self-awareness.
• Ability to thrive in a fast-paced environment with strong ability to handle multiple activities simultaneously, prioritizing and pivoting as necessary.
• Passion for helping patients and developing transformative treatments; motivated by patient focus and personal commitment to high performance and results.

Pay

U.S. Pay Range: $177,500.00 - $240,100.00. The pay range reflects the full-time base salary range expected for this role at the time of posting. Base pay will be determined based on relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).

Benefits

• Comprehensive medical, dental, and vision coverage.
• Life and disability insurance.
• Lifestyle reimbursement program.
• Flexible spending and health savings accounts.
• 401(k) with a generous company match.
• Paid time off, wellness days, holidays, and two company-wide recharge breaks.
• Generous family resources and leave.

About Alnylam

Alnylam is the leader in RNAi therapeutics—a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered breakthroughs that made RNAi therapeutics possible and continues to pioneer the field. The company’s deep pipeline and late-stage programs reflect core values: fierce innovation, passion for excellence, purposeful urgency, open culture, and commitment to people. Alnylam is a globally recognized top employer with an authentic, inclusive culture where breakthrough thinking fuels success.