Advisor, Drug Product Process Development

About the role

The successful candidate will design, execute, and oversee experiments for the technical development and scale-up of lipid nanoparticle (LNP) drug product processes. This role offers a unique opportunity to independently drive LNP platform science within Orna, identify knowledge gaps, and translate cutting-edge formulation science into robust, scalable manufacturing processes.

Responsibilities

• Design, execute, and oversee experiments for the technical development and scale-up of lipid nanoparticle (LNP) drug product processes.
• Independently drive LNP platform science within Orna, identify knowledge gaps, and translate cutting-edge formulation science into robust, scalable manufacturing processes.
• Possess excellent oral and written communication capabilities, demonstrate strong collaboration and interpersonal skills, and be adept at problem solving in a fast-paced, innovation-driven environment.

Requirements

• PhD, MS, or BS degree in chemical engineering, biomedical engineering, pharmaceutical sciences, chemistry, biology, or a related field with the following years of industry experience: PhD 0-5 years, MS 7+ years, or BS 10+ years.
• Demonstrated hands-on experience in formulation and process development particularly in carrier-based or complex drug product systems (e.g., lipid nanoparticles, liposomes, emulsions, microspheres, or other advanced delivery platforms).
• Working knowledge of fluid mixing dynamics, particle self-assembly, and surface chemistry concepts, including common characterization methods (e.g. DLS, Ribogreen, Cryo-EM etc.).
• Track record of independently designing and executing experiments; ability to proactively identify scientific knowledge gaps and propose structured plans to address them.

Additional Preferences

• Experience with multiple filtration technologies such as TFF hollow fibers, flat sheets, and depth filtration a plus.
• Experience working within a matrixed CMC environment, including cross-functional collaboration with manufacturing, analytical development, and formulation development teams.
• Strong oral and written communication skills; ability to present complex technical information clearly to diverse audiences.
• Organized, collaborative, and able to effectively partner with a diverse group of scientists, engineers, and external stakeholders.
• Proven ability to work on cross-functional teams in a fast-paced, dynamic environment, managing multiple priorities simultaneously.
• Detail-oriented, self-motivated, and enthusiastic about taking on new scientific and technical challenges.

Basic Requirements

• PhD, MS, or BS degree in chemical engineering, biomedical engineering, pharmaceutical sciences, chemistry, biology, or a related field with the following years of industry experience: PhD 0-5 years, MS 7+ years, or BS 10+ years.
• Demonstrated hands-on experience in formulation and process development particularly in carrier-based or complex drug product systems (e.g., lipid nanoparticles, liposomes, emulsions, microspheres, or other advanced delivery platforms).
• Working knowledge of fluid mixing dynamics, particle self-assembly, and surface chemistry concepts, including common characterization methods (e.g. DLS, Ribogreen, Cryo-EM etc.).
• Track record of independently designing and executing experiments; ability to proactively identify scientific knowledge gaps and propose structured plans to address them.