Advisor, Drug Product Process Development

About the role

The successful candidate will design, execute, and oversee experiments for the technical development and scale-up of lipid nanoparticle (LNP) drug product processes. This role offers a unique opportunity to independently drive LNP platform science within Orna, identify knowledge gaps, and translate cutting-edge formulation science into robust, scalable manufacturing processes.

Responsibilities

• Design, execute, and oversee experiments for the technical development and scale-up of lipid nanoparticle (LNP) drug product processes.
• Independently design and execute experiments; ability to proactively identify scientific knowledge gaps and propose structured plans to address them.
• Develop and optimize LNP drug product processes, including formulation and process development.
• Collaborate with cross-functional teams, including manufacturing, analytical development, and formulation development teams, to ensure seamless integration of LNP technology into the production pipeline.
• Contribute to the advancement of Orna’s LNP platform science by identifying and addressing knowledge gaps in the field.

Requirements

• PhD, MS, or BS degree in chemical engineering, biomedical engineering, pharmaceutical sciences, chemistry, biology, or a related field with the following years of industry experience: PhD 0-5 years, MS 7+ years, or BS 10+ years.
• Demonstrated hands-on experience in formulation and process development particularly in carrier-based or complex drug product systems (e.g., lipid nanoparticles, liposomes, emulsions, microspheres, or other advanced delivery platforms).
• Working knowledge of fluid mixing dynamics, particle self-assembly, and surface chemistry concepts, including common characterization methods (e.g. DLS, Ribogreen, Cryo-EM etc.).

Qualifications

• Strong background in carrier-based drug product development, process optimization, scale-up, and technical transfer.
• Excellent oral and written communication capabilities.
• Strong collaboration and interpersonal skills.
• Adept at problem-solving in a fast-paced, innovation-driven environment.