173893

Piper Companies is seeking a Clinical Research Associate II to join a global organization within the clinical research and life sciences industry for a remote permanent role with 60-75% travel across the United States. This CRA II will support cardiovascular, CNS, and metabolic studies while partnering closely with investigative sites to ensure high-quality trial execution. Responsibilities of the Clinical Research Associate II include: Perform routine and close-out monitoring visits to ensure studies are conducted in alignment with GCP, ICH, and applicable regulations. Serve as the primary point of contact for assigned research sites, fostering strong relationships and ongoing communication. Review site data, source documentation, and regulatory files to confirm accuracy, completeness, and protocol adherence. Provide guidance and training to site staff on protocol requirements, study procedures, and compliance expectations. Identify, document, and escalate quality or compliance concerns while supporting resolution efforts. Qualifications for the Clinical Research Associate II include: 1–4 years of onsite clinical monitoring experience, aligned to CRA II or Senior CRA I level. Experience supporting clinical trials within cardiovascular, CNS, diabetes, or metabolic indications. Strong working knowledge of GCP, ICH guidelines, and FDA regulatory requirements. Proficiency with CTMS, EDC systems, and standard clinical trial documentation. Bachelor’s degree in life sciences, nursing, or a related discipline; Spanish fluency is highly preferred for candidates based in Florida or Puerto Rico. Compensation for the Clinical Research Associate II: Salary Range: $100,000–$125,000/year (USD) Comprehensive Benefits: Medical, Dental, Vision, sick leave if required by law, and 401(k) This job opens for applications on 8/31/26. Applications for this job will be accepted for at least 30 days from the posting date. Keywords: clinical research, clinical trials, CRA, GCP, ICH, regulatory compliance, site monitoring, clinical monitoring, CTMS, EDC, cardiovascular studies, CNS trials, diabetes research, GLP-1, site management, FDA regulations, clinical operations, documentation, quality assurance, protocol compliance, investigator sites, patient safety, clinical development.