VP, Program Management

Responsibilities

• Own the integrated program plan.
• Build and maintain a single, authoritative view of timelines, milestones, dependencies, and the critical path across all functions for PIKTOR and, over time, the broader portfolio.
• Make the interdependencies between functions visible and actively managed rather than discovered late.
• Serve as the source of truth for where each program stands and what is about to change.
• Proactively surface roadblocks, slippage, and any new information that could affect readouts or timelines to the ELT and C-suite — early, clearly, and with options, not just problems.
• Run the decision-making machinery.
• Design and own the governance model — core team cadence, stage gates, decision rights, and escalation paths — so that strategic decisions are framed and surfaced early.
• Draft OKRs, prepare and drive toward key decision points in partnership with the functional leaders who own them.
• Surface strategy early and prepare the materials to support it.
• Work alongside functional leaders to anticipate the strategic choices coming down the pipeline, frame the options and trade-offs, and help build the materials that let the CEO and ELT decide well.
• Act as a strategic thought partner and right hand to the CEO on program direction — with a clear path to growing into de facto asset leadership as the company scales.
• Manage program budget and resources.
• Track program-level budget, resourcing, and CRO/vendor coordination in partnership with Finance, with dual responsibility alongside Clinical Operations for the clinical-development portions of the plan.
• Quarterback business development execution.
• As partnership and corporate-development conversations progress, serve as the internal quarterback of diligence and deal readiness — coordinating cross-functional inputs, keeping the company “diligence-ready,” and ensuring a coherent, defensible data package.
• Support board and investor readiness.
• Help prepare program-related board and investor materials and keep externally communicated timelines honest against the internal integrated plan.
• Lead through influence, not authority.
• Drive alignment and execution across functions you don't directly manage.
• Build the trust and credibility that let you hold senior, expert colleagues to shared commitments and timelines.
• Support board and investor readiness.
• Help prepare program-related board and investor materials and keep externally communicated timelines honest against the internal integrated plan.
• Lead through influence, not authority.
• Drive alignment and execution across functions you don't directly manage.
• Build the trust and credibility that let you hold senior, expert colleagues to shared commitments and timelines.
• Support board and investor readiness.
• Help prepare program-related board and investor materials and keep externally communicated timelines honest against the internal integrated plan.
• Lead through influence, not authority.
• Drive alignment and execution across functions you don't directly manage.
• Build the trust and credibility that let you hold senior, expert colleagues to shared commitments and timelines.
• Support board and investor readiness.
• Help prepare program-related board and investor materials and keep externally communicated timelines honest against the internal integrated plan.

  Qualifications

  • ~10+ years in biotech/pharma drug development, with meaningful time in a program or portfolio management capacity.
  • Direct experience taking a program through late-stage development and to approval and/or commercialization.
  • Oncology strongly preferred; familiarity with small-molecule and/or PI3K/AKT/mTOR pathway programs is a plus.
  • Demonstrated ability to lead complex, cross-functional programs and influence senior executives without direct authority — a proven balance of strategic leadership and hands-on execution, with a bias toward execution and closure.
  • Deep, hands-on command of the integrated drug-development process across functions (clinical development, clinical operations, regulatory, CMC, nonclinical, finance, legal).
  • Genuinely AI-native: already using AI tools extensively in your daily work and eager to push further.
  • Comfortable designing and iterating on dashboards, reporting, and communication tooling yourself.
  • Exceptional communication, facilitation, and executive-presentation skills; able to synthesize complexity into clear, decision-ready narratives.
  • Experience supporting business development / corporate development diligence, alliance management, or partnership execution is a strong plus.
  • Traits: Thrives in a small, fast-moving, ambiguous environment; low-ego, collaborative, and comfortable being the person who makes sure nothing gets missed.
  • Experience preparing board- or investor-facing materials is a plus.

    Pay

    Compensation Range: $270,000 - $350,000 (actual compensation may vary based on experience, qualifications and location)

    Benefits

    • Competitive salary and equity in a well-funded, clinical-stage biotech
    • 100% remote work and flexible schedule
    • Health, dental, and vision for you and your dependents
    • Flexible time off
    • Generous parental leave
    • Traditional and Roth 401k
    • Mission oriented, remote first culture
    • We are an equal opportunity employer, and we value diversity at our company.
    • We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
    • All offers of employment are contingent upon satisfactory completion of a background check and verification of eligibility to work in the United States.