VP, Global Manufacturing and Supply Chain

Position Summary

As we continue to advance our innovative product pipeline and progress our lead obesity development program towards commercialization and launch, we are seeking a Vice President, Global Manufacturing & Supply Chain reporting to the SVP of Technical Operations to lead our end-to-end manufacturing, supply chain and commercial readiness activities.

Key Responsibilities

• External Manufacturing

  • Develop and lead the external manufacturing strategy across DS, DP, and packaged/finished product to support global clinical trials and commercial supply.
  • Establish external manufacturing team, process, governance, KPIs, working agreements and business review cadence with partnership mindset and monitor execution and ongoing production performance.
  • Ensure reliable execution of manufacturing operations to meet PDUFA, launch, and ongoing supply needs—including campaign planning, batch release, and issue resolution.
  • Lead CDMO governance and relationship management, including executive-level interactions, KPIs, and escalation pathways.
  • Serve as the executive leader and primary point of accountability for CDMO performance, including quality, timelines, cost, and compliance.
  • Partner with Quality and Regulatory to ensure GMP compliance, inspection readiness, and alignment with global regulatory expectations.
  • Collaborate cross-functionally with CMC Development, Quality, Supply Chain, and Regulatory to align on technical transfers, validation strategies, and lifecycle management.
  • Proactively identify risks and implement mitigation plans to ensure continuity and robustness of external manufacturing operations.
  • Provide strategic input into make/buy decisions, site selection, and future-state network design.
  • Support business development and sourcing efforts related to manufacturing.

• Global Supply Chain and Commercial Readiness

  • Oversee supply of clinical trial materials across global studies in alignment with Clinical Operations, CMC, and Regulatory teams.
  • Direct global demand forecasting, supply planning, and inventory strategies to support clinical and commercial needs.
  • Lead commercial launch execution activities within Tech Ops.
  • Ensure adequate capacity planning, tech transfer, and commercial-scale readiness in coordination with Technical Operations and Quality.
  • Select and implement the necessary planning and performance/risk monitoring tools to enhance visibility and data availability within the supply chain.
  • Oversee global logistics and distribution, 3PL selection and oversight, serialization and anticounterfeiting programs and ensure compliance with all global trade regulations.
  • Carry out an interim global PM role as Structure grows & help develop timelines and key activities.

Qualifications

• Minimum bachelor’s degree in supply chain, Engineering, or related field (MBA preferred).

• 20+ years of progressive leadership experience in biopharmaceutical manufacturing, supply chain, technical operations with at least 5+ years’ experience in external CDMO management.

• Proven success in building or scaling manufacturing and supply chain teams and leading new product launches.

• Deep understanding of GMP compliance, Regulatory CMC expectations and global supply chain requirements.

• Experience with small molecule API manufacturing, oral solid dosage forms and combination products.

• Deep understanding of GMP, GDP, and international regulatory requirements, with launch readiness experience in the U.S. and EU markets.

• Excellent business acumen and demonstrated ability to think strategically and ensure excellence in execution in complex programs operation under tight timelines and budgets.

• Excellent leadership, communication, and cross-functional collaboration skills.

• Ability to influence internal and external stakeholders.

• Partnership mindset and ability to build relationships with key partners in Quality, Regulatory, CMC, Technical Operations, R&D and Commercial functions.

• Demonstrated success in building scalable teams, leading complex projects and driving accountability in matrixed organizations.