Vice President, Translational Research

About the role

The Vice President will lead the Cancer Pharmacology function at Revolution Medicines, a late-stage clinical oncology company focused on RAS(ON) inhibitors for RAS-addicted cancers. This role will involve collaborating with colleagues in Research and Development to deliver mechanistic, efficacy, PK/PD, and combination strategy insights that enable candidate selection, IND-enabling studies, translational biomarker strategies, and clinical development decisions.

Responsibilities

• Define and implement forward translation strategies for RAS-driven diseases
• Supervise an internal team of highly experienced and accomplished cancer pharmacologists to drive in vivo pharmacology in parallel with scientific discovery and combination strategies
• Drive efforts to organize and harmonize large data sets across the organization, as part of a digital data transformation initiative
• Champion the integration of advanced computational approaches, AI/ML methodologies, and modern data infrastructure to enable data-driven decision making across discovery, translational research, and development
• Be accountable for a sophisticated core operations group that can meet diverse needs across research, including international preclinical CRO management and internal regulatory and operational interactions
• Leverage strong cross-functional skills to develop productive collaborations with diverse groups across the organization including research, development, and project teams
• Engage with external collaborations including academic centers, CROs, non-profit organizations and experts to drive execution of key projects and bring in new technologies
• Represent Revolution Medicines externally through scientific publications, conference presentations, advisory boards, and strategic collaborations
• Be a strategic leader and thought partner for disease area strategy initiatives to accelerate our pipeline, stay up to date with industry trends to identify future translational gaps and opportunities, and develop plans to implement and help programs pivot to ensure future success

Requirements

PhD in oncology, pharmacology, cancer biology, molecular biology, or related discipline, and background in the principles of oncology. 12+ years of experience in oncology drug discovery, ideally as a pharmacologist with expertise in PK/PD/efficacy for drug development in a life sciences environment. Experience advancing small molecule oncology programs from discovery through IND and early clinical development. Demonstrated success leading and developing high-performing scientific organizations and managing experienced scientific leaders. Experience working at the interface between discovery and development within the oncology field is essential. Strong strategic management/coordination skills, with the ability to develop project roadmaps, manage timelines, and align key stakeholders across departments. Computational biology skills and/or experience with large data mining; familiarity with life science software platforms (e.g. Benchling), cloud-based storage, integration, and compute infrastructures. Exceptional communication, collaboration, and leadership abilities, particularly in tackling complex projects involving diverse scientific, technical, and leadership teams.

Qualifications

PhD in oncology, pharmacology, cancer biology, molecular biology, or related discipline, and background in the principles of oncology. 12+ years of experience in oncology drug discovery, ideally as a pharmacologist with expertise in PK/PD/efficacy for drug development in a life sciences environment. Experience advancing small molecule oncology programs from discovery through IND and early clinical development. Demonstrated success leading and developing high-performing scientific organizations and managing experienced scientific leaders. Experience working at the interface between discovery and development within the oncology field is essential. Strong strategic management/coordination skills, with the ability to develop project roadmaps, manage timelines, and align key stakeholders across departments. Computational biology skills and/or experience with large data mining; familiarity with life science software platforms (e.g. Benchling), cloud-based storage, integration, and compute infrastructures. Exceptional communication, collaboration, and leadership abilities, particularly in tackling complex projects involving diverse scientific, technical, and leadership teams.

Skills

Project team leadership experience. Experience coordinating the curation, ingestion, and harmonization of legacy scientific data across internal, external, public, and licensed data sources. Ability to work in a high-energy, fast-paced, rapidly evolving and scaling company, operating in a highly competitive field.

Benefits

Base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is $294,000 - $367,000 USD. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.