Jobs · Management · Massachusetts

US Director of Supply Chain & Logistics

AdvanCell · Andover, MA · 1 mo ago
On-siteManagementFull-time

About the role

The Director of Supply Chain and Logistics is responsible for leading site-wide supply chain operations, including procurement, production planning, inventory management, warehousing, incoming sampling, and logistics to ensure the reliable manufacture, supply, and delivery of Pb-212 radiopharmaceuticals. The role oversees demand planning, material management, MRP/ERP systems and master data governance, and supply chain risk management to support uninterrupted operations and regulatory compliance. The incumbent translates demand forecasts into executable production and supply plans, drives continuous improvement, and develops scalable systems, processes, and organizational capabilities to support clinical and future commercial operations. Working closely with clinical supply teams, contract manufacturing organizations, and logistics providers, the role ensures effective end-to-end supply chain execution. As a member of the Andover Site Leadership Team, the Head of Supply Chain and Logistics contributes to strategic planning, organizational development, and cross-functional decision-making to achieve business objectives and support the site's growth into full GMP manufacturing. Success in this role requires strong leadership, collaboration, adaptability, and the ability to drive results in a dynamic and evolving environment.

Responsibilities

  • Lead end-to-end clinical supply chain planning and execution, including production scheduling, isotope availability, inventory management, and distribution to ensure uninterrupted product supply
  • Oversee materials planning, procurement, warehouse operations, and logistics to support just-in-time (JIT) delivery of Pb-212 radiopharmaceutical products
  • Own site-wide planning processes, including demand and supply planning, safety stock strategies, and integration of supply chain requirements into business and strategic plans
  • Drive cross-functional supply chain governance and issue resolution, proactively addressing supply risks, shortages, delays, and vendor-related challenges
  • Develop and maintain planning systems, dashboards, KPIs, and master data governance (materials, BOMs, recipes, and resources) to enable effective decision-making and operational control
  • Lead operational excellence initiatives focused on performance management, resource optimization, risk mitigation, continuous improvement, and supply reliability
  • Build organizational capability and readiness for GMP manufacturing operations, supporting scale-up, technology transfer, facility expansion, and commercialization activities
  • Partner with Quality, Regulatory, R&D, CMC, Clinical, Engineering, and Infrastructure teams to execute manufacturing strategies and achieve site objectives
  • Oversee supply agreements and collaborate with Quality and Legal teams on contract management and negotiations
  • Ensure compliance with cGMP, FDA, DOT,

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