Toxicology Research Associate - Preclinical Safety assessment

Company Description

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier, and more sustainable. Founded in 1992, Eurofins has grown from one laboratory in Nantes, France to over 47,000 staff across a network of more than 900 independent companies in over 50 countries and operating more than 800 laboratories. Eurofins offers a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability, and purity of biological substances and products, as well as providing innovative clinical diagnostic testing services. In 2021, Eurofins generated total revenues of EUR 6.72 billion, and has been among the best performing stocks in Europe over the past 20 years.

About the role

Job Description

Eurofins PSS is seeking a highly motivated Research Associate to support our client located in Boston, MA. This individual will support the client’s In Vitro Toxicology group, where a team of toxicologists and safety pharmacologists work to design human and preclinical animal in vitro models to support prioritization and de-risking of novel therapeutic agents throughout the drug discovery and development process. The ideal candidate will have a strong scientific background in the culture and maintenance of human cells, such as human iPSC-derived cardiomyocytes, to model tissues and organs for drug screening and mechanism of action experiments to support drug discovery projects. Proficiency in various molecular and cellular technical skills is required.

• Culture of complex human cellular models for drug screening and proof-of-mechanism studies
• Contribute to the development and implementation of in vitro assays to support the selection and de-risking of potential drug candidates through close interactions with discovery toxicologists, medicinal chemists, and research functions
• Conduct and report results from the tiered strategy toxicological profiling experiments
• Work closely with cross-functional teams to conceive, develop, and deploy bespoke organotypic investigative/screening assays to better inform on potential safety liabilities

Responsibilities

Culture of complex human cellular models for drug screening and proof-of-mechanism studies

Contribute to the development and implementation of in vitro assays to support the selection and de-risking of potential drug candidates through close interactions with discovery toxicologists, medicinal chemists, and research functions

Conduct and report results from the tiered strategy toxicological profiling experiments

Work closely with cross-functional teams to conceive, develop, and deploy bespoke organotypic investigative/screening assays to better inform on potential safety liabilities

Qualifications

• Minimal Requirements: BS with 1-2 years of relevant work experience or MS degree with 0-1 years of relevant work experience, and relevant experience in Cell Biology, Molecular Biology or a related discipline
• Strong technical understanding of general laboratory techniques
• Extensive experience in cell culture and sterile techniques is required
• Excellent multi-tasking skills, attention to detail, and ability to work independently
• Maintains accurate and reliable record keeping, including database management, notebooks, and all other pertinent documentation

Authorization to work in the United States indefinitely without restriction or sponsorship

The Ideal Candidate Will Have Experience working with high-throughput plate formats and automated liquid handling preferred

A desire to be in a highly innovative environment aimed at transforming the lives of people with serious diseases, their families, and society

Benefits

• What To Expect In The Hiring Process
• 10-15 Minute Phone Interview with Region Recruiter
• 45-60 Minute Virtual Interview with Manager and/or Group Leader
• 60 Minute Onsite Meeting

Additional Information

The position can be full-time, Monday through Friday, 8 am-5 pm. Candidates living within commutable distance of Boston, MA, are encouraged to apply. Excellent Full-time Benefits Include:

• Base comp: $30-34/hr
• Comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays

Additional Details

Eurofins Lancaster Laboratories Professional Scientific Services® (PSS) is a global, award-winning insourcing solution that places our people at our clients’ sites, dedicated to running and managing laboratory services while eliminating headcount, co-employment, and project-management worries. We infuse our 55-year track record of scientific and laboratory operations expertise, as well as HR and great place to work best practices, to recruit, hire, train, and manage highly qualified scientists to perform laboratory services using our clients’ quality systems and equipment.