Jobs · Engineering · California

Technical Lead - Software Developer, Data Foundry

BioSpace · San Francisco, CA · 1 mo ago
Engineering$152k–$244k/yrFull-time

Responsibilities

  • Design, build, and maintain data processing pipelines for complex scientific datasets (chemical, biological, HTE, and automation-generated data), ensuring FAIR compliance and machine-actionability.
  • Develop RESTful APIs and microservices providing unified programmatic access to LIMS, ELNs, instruments, data warehouses (Postgres, Redshift, Snowflake), and analytical databases.
  • Support continuous improvement of LIMS and adjacent systems to meet evolving scientific workflows, security, and scalability standards.
  • Build ML deployment pipelines—experiment tracking, model versioning (MLflow, W&B), containerized serving, monitoring, and automated retraining.
  • Implement model observability: drift detection, performance alerting, and lifecycle management.
  • Collaborate with Methods4Insight to operationalize cheminformatics, statistical, and AI/ML models as production APIs.
  • Develop agent-ready APIs with structured error handling, audit trails, and monitoring supporting agent autonomy and human oversight.
  • Create modular, reusable automation workflow components scientists can configure without writing code.
  • Work directly with bench scientists to rapidly prototype custom applications, dashboards, and workflow tools to improve scientist's experience and efficiency.
  • Validate prototypes through iterative scientist feedback, then partner with Tech@Lilly to hand off for enterprise scaling with defined transition criteria and documentation.
  • Build and operate cloud-native components (AWS, Azure, or GCP) supporting containerized workflows (Kubernetes/Docker), infrastructure-as-code, CI/CD, and workflow orchestration (Prefect, Airflow, Nextflow).
  • Apply DevSecOps standards including security scanning, code review, and automated testing.

Requirements

  • B.S./M.S/Phd. in Computer Science, Bioinformatics, Computational Biology, Cheminformatics, Chemistry, Biology, Biomedical Engineering, or related STEM field.
  • BS (with 10+years), MS (with 5+ years) or Phd (1+ year) of scientific software development experience, with understanding of experimental data types and scientific workflows.
  • Proficiency in Python and at least one additional language (Java, C#, Go, TypeScript, or Rust); strong SQL skills.
  • Experience building RESTful APIs, data pipelines, and/or microservices for scientific or technical applications.
  • Pharmaceutical or biotech research industry experience, particularly in discovery workflows for biology, chemistry, biochemistry or automation.
  • MLOps tooling: experiment tracking (MLflow, W&B), model registries, model serving, monitoring/drift detection.
  • Familiarity with cloud platforms (AWS, Azure, or GCP), containerization (Docker/Kubernetes), and Git.
  • Strong communication skills with a track record of productive scientist collaboration.
  • Exposure to AI agent infrastructure, MCP frameworks, or building APIs that AI/ML systems invoke programmatically.
  • Experience integrating lab automation systems with digital platforms or AI-driven workflows.
  • Hands-on experience with cheminformatics tools (RDKit, Schrödinger, MOE) or bioinformatics platforms.
  • Data warehousing experience (Postgres, Redshift, BigQuery, Snowflake) and scientific data standards/ontologies.
  • LIMS/ELN experience (e.g., Benchling) and laboratory instrument integration.
  • Workflow orchestration (Prefect, Airflow, Nextflow, WDL), CI/CD, and Linux/bash scripting.
  • Strong learning agility—willingness to step outside comfort zone and adopt new technologies to get the job done.

Qualifications

  • BS (with 10+years), MS (with 5+ years) or Phd (1+ year) of scientific software development experience, with understanding of experimental data types and scientific workflows.
  • Proficiency in Python and at least one additional language (Java, C#, Go, TypeScript, or Rust); strong SQL skills.
  • Experience building RESTful APIs, data pipelines, and/or microservices for scientific or technical applications.
  • Pharmaceutical or biotech research industry experience, particularly in discovery workflows for biology, chemistry, biochemistry or automation.
  • MLOps tooling: experiment tracking (MLflow, W&B), model registries, model serving, monitoring/drift detection.
  • Familiarity with cloud platforms (AWS, Azure, or GCP), containerization (Docker/Kubernetes), and Git.
  • Strong communication skills with a track record of productive scientist collaboration.
  • Exposure to AI agent infrastructure, MCP frameworks, or building APIs that AI/ML systems invoke programmatically.
  • Experience integrating lab automation systems with digital platforms or AI-driven workflows.
  • Hands-on experience with cheminformatics tools (RDKit, Schrödinger, MOE) or bioinformatics platforms.
  • Data warehousing experience (Postgres, Redshift, BigQuery, Snowflake) and scientific data standards/ontologies.
  • LIMS/ELN experience (e.g., Benchling) and laboratory instrument integration.
  • Workflow orchestration (Prefect, Airflow, Nextflow, WDL), CI/CD, and Linux/bash scripting.
  • Strong learning agility—willingness to step outside comfort zone and adopt new technologies to get the job done.

Skills

  • Python
  • Additional languages (Java, C#, Go, TypeScript, or Rust)
  • SQL
  • RESTful APIs
  • Data pipelines
  • Microservices
  • Machine Learning
  • Model deployment
  • Model observability
  • Cloud platforms (AWS, Azure, or GCP)
  • Containerization (Docker/Kubernetes)
  • Git
  • Communication skills
  • AI agent infrastructure
  • MCP frameworks
  • Lab automation systems
  • Cheminformatics tools (RDKit, Schrödinger, MOE)
  • Bioinformatics platforms
  • Data warehousing (Postgres, Redshift, BigQuery, Snowflake)
  • LIMS/ELN experience (e.g., Benchling)
  • Workflow orchestration (Prefect, Airflow, Nextflow, WDL)
  • CI/CD
  • Linux/bash scripting
  • Learning agility

Benefits

Not specified

Pay

$151,500 - $244,200

Schedule

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).

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