Sr. Scientist, Viral Vector
Kite Pharma · San Francisco Bay Area · 2 wk ago
Information Technology$169k–$219k/yrFull-time
Key Responsibilities
- Lead and manage a vector core team to produce lenti and retroviral vectors supporting Research teams and activities in the organization.
- Lead experimental design and execution for lentiviral and viral vector–based gene delivery strategies supporting CAR-T, TCR-T, and emerging gene therapy modalities.
- Exceptional record keeping and Lab information management system policy adherence.
- Develop, optimize, and characterize viral vector production, for in vivo and ex vivo lentiviral systems.
- Apply deep understanding of viral biology, vector engineering, and gene expression control to improve efficiency, safety, and scalability.
- Serve as a technical expert for viral delivery, providing guidance to discovery, translational, and process development teams.
- Collaborate cross-functionally with Research teams, core groups, analytical development, process development, and regulatory partners.
- Interpret complex datasets, troubleshoot experimental challenges, and drive data-driven decision making.
- Author technical reports, protocols, and contribute to IND-enabling documentation as needed.
- Present results at internal forums and external scientific meetings.
- Mentor direct reports and contribute to building best practices within the viral vector group.
Basic Qualifications
- Advanced scientific degree (MD, PharmD, PhD) in Molecular Biology, Cell Biology, Virology, Bioengineering, or a related field, with 2+ years of relevant postdoctoral or industry experience.
- OR Master’s degree in Molecular Biology, Cell Biology, Virology, Bioengineering, or a related field, with 6+ years of relevant scientific experience.
- OR Bachelor’s degree in Molecular Biology, Cell Biology, Virology, Bioengineering, or a related field, with 8+ years of relevant scientific experience.
Preferred Qualifications
- Ph.D. in Molecular Biology, Cell Biology, Virology, Bioengineering, or a related field, with 3+ years of relevant postdoctoral or industry experience.
- Demonstrated, hands-on expertise in lentiviral vector design, optimization, production, and transduction.
- Strong background in viral gene delivery for cell or gene therapy applications.
- Proven ability to work in a highly matrixed environment.
- Deep knowledge of mammalian cell culture, transfection/transduction methods, and molecular biology techniques (e.g., ddPCR, qPCR, flow cytometry, Western blot, ELISA).
- Proven ability to independently design and execute complex experiments.
- Strong written and verbal communication skills.
- Experience supporting CAR-T or engineered cell therapy programs.
- Knowledge of non-lentiviral viral systems (e.g., retroviral, AAV vectors).
- Experience with scale-up, process development, or tech transfer of viral vectors.
- Experience with high throughput screening, automation, and use of liquid handlers (Biomek, TECAN etc).
- Experience with viral vector producer cell line improvement and optimization strategies.
- Track record of publications, patents, or successful program contributions.
Key Competencies
- Scientific rigor and experimental excellence.
- Cross-functional collaboration and leadership.
- Strategic thinking with attention to detail.
- Ability to thrive in a fast-moving, results-driven environment.
Pay Range
The salary range for this position is: $169,320.00 - $219,120.00. Kite considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary.
Benefits
This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans. For additional benefits information, visit: https://www.gilead.com/careers/compensation-benefits-and-wellbeing.