Sr. Scientist I (Pre-formulation and Solid State Characterization)

About the role

The Discovery & Development team is driven by our patient-first commitment to advancing a retinal disease-focused pipeline. This function leads end-to-end R&D, from early discovery through product development, leveraging cutting-edge ophthalmology and biotechnology platforms to deliver innovative therapeutics that protect vision.

Responsibilities

• Work in close partnership with Drug Substance, Analytical Development, and Formulation Development to progress API from discovery to manufacturing.
• Contribute to a thorough understanding of drug substance attributes, such as solubility, polymorphism, morphology, and stability and conceive formulation strategy.
• Design and execute crystallization process with a focus on form control, particle size/morphology, yield, purity, and process understanding.
• Identify and deploy new solid state characterization technologies as needed.
• Prepare pre-formulation and pharmaceutical development reports and other technical documentation required for regulatory submissions.
• Maintain an understanding of current laws & regulations applicable to the pharmaceutical/biotechnology industry.

Requirements

• Expertise in pre-formulation development of small molecules.
• Strong lab skills with a Can-Do attitude; independently carry out pre-formulation research.
• Highly skilled in characterization techniques such as PLM, SEM, PXRD, TGA, DSC, DVS, NMR, FTIR, Raman, and UV/Vis.
• Skilled in independently organizing project goals and completing long-term projects on time.
• Flexible, adaptable and collaborative style with a willingness to take on new challenges and positively respond to changes.
• Possess high integrity and exceptional work ethic.
• Excellent interpersonal, technical writing, and oral communication skills.
• A team player, collaborating effectively with a broad range of internal functions.
• Versatile, driven and curious to take on new and challenging roles and responsibilities.

Qualifications

• PhD or Master in Material Sciences, Pharmaceutical Sciences or related discipline.

Skills

• Expertise in pre-formulation development of small molecules.
• Strong lab skills with a Can-Do attitude; independently carry out pre-formulation research.
• Highly skilled in characterization techniques such as PLM, SEM, PXRD, TGA, DSC, DVS, NMR, FTIR, Raman, and UV/Vis.
• Skilled in independently organizing project goals and completing long-term projects on time.
• Flexible, adaptable and collaborative style with a willingness to take on new challenges and positively respond to changes.
• Possess high integrity and exceptional work ethic.
• Excellent interpersonal, technical writing, and oral communication skills.
• A team player, collaborating effectively with a broad range of internal functions.
• Versatile, driven and curious to take on new and challenging roles and responsibilities.

Benefits

Envision Your Future With the exciting energy of a winning culture and an exhilarating pace, we are an ophthalmology company committed to preventing blindness by developing and commercializing innovative therapeutics. The collective power of our values influences everything we do, and everything we do for you.

Schedule

Based in Watertown, MA and reporting to the Senior Director of Formulation Development, this position is full-time.

Pay

$146,260 - $184,713 USD