Jobs · Analyst · California

Sr Scientist I - Biopharmaceutics

AbbVie · South San Francisco, CA · 1 mo ago
AnalystFull-time
We need to output HTML fragment with sections: About the role? Actually we need to reformat job posting into clean semantic HTML. Use

for section headings (e.g. About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule). Use
  • for any list of duties/requirements/benefits, and

    for prose. Do NOT repeat the job title as a heading (the page already shows it) and do NOT put Job ID / requisition numbers as headings — fold minor metadata into a short

    or drop it. Preserve ALL substantive information; do NOT invent or summarize away detail. Remove cookie/navigation/legal/EEO/equal-opportunity/scam-warning boilerplate, duplicated lines, and application instructions. IMPORTANT: include a section ONLY when the posting has real, specific content for it — never emit a heading followed by filler/placeholder text (e.g. "commensurate with experience", "not specified", "N/A", "varies", "TBD") and never create Pay/Schedule/Benefits sections unless the posting actually states them. Prefer a few substantive sections over many thin ones. Output ONLY the HTML fragment — no /, no markdown code fences. We need to parse the given posting. The posting includes: Company Description About AbbVie ... (some description). Then Job Description (multiple paragraphs). Then Job Description again (duplicate?). Then Qualifications. Then Additional Information (benefits, pay range, etc). Then EEO boilerplate. We need to remove boilerplate: company description maybe considered not boilerplate? It's about AbbVie. Might be considered part of job posting but not required? The instruction: "Remove cookie/navigation/legal/EEO/equal-opportunity/scam-warning boilerplate, duplicated lines, and application instructions." Company description is not explicitly listed to remove, but it's generic description of company; maybe we keep? However they said "Preserve ALL substantive information". Company description is substantive? It's about AbbVie mission etc. Might be considered part of job posting but not essential to role. Usually they'd keep it. But we can decide to keep a short paragraph about AbbVie as part of "About the company" maybe not a required heading. Since we only have headings for sections like About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule. We could map content accordingly. We need to decide which sections to include based on content. Content: - About AbbVie (company description) maybe could go under "About the role"? Not exactly. Could be a short paragraph before sections. - Job Description: description of MPDD function, responsibilities, what they do. This is responsibilities. - Then second Job Description: more specifics about role: Senior Scientist I, lead peptide oral delivery programs, lead CMC developability assessment, etc. This also responsibilities/requirements. - Qualifications: education, experience, preferred backgrounds, fundamental understanding, familiarity, experience, knowledge, skills. - Additional Information: compensation range, benefits, short-term incentive programs, note about pay, EEO. We need to include Benefits and Pay sections only if posting actually states them. It does state benefits: "We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees. This job is eligible to participate in our short-term incentive programs." Also compensation range described: "The compensation range described below is the range of possible base pay compensation..." So we have pay info. Thus we should include a Benefits section (with ul list) and a Pay section (maybe just a p with the range). Also maybe a Schedule section? Not present, so omit. We also need About the role? Could be a short paragraph summarizing role. Could combine responsibilities and qualifications? But we need to follow headings: About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule. We have responsibilities (duties). We have qualifications (education/experience). We have skills (maybe separate from qualifications? Could combine). The posting includes skills like communication, self-management, etc. Could put under Skills. We need to avoid duplication. Let's extract substantive content: Company description: Could be placed as a brief intro before sections, maybe as a

    without heading. Responsibilities: from job description paragraphs. Let's list responsibilities: - Utilize state of the art automation and computational tools supported by expertise in biopharmaceutics, drug delivery, and solid-state chemistry to collaboratively progress candidates with higher probability of success into development and advise clinical formulation strategy. - Identify the commercial solid form of the active pharmaceutical ingredient (API) and establish structure-property-performance correlations to help deliver robust commercial processes and align control strategies across drug substance and product. - Transition drug substance isolation processes and relevant physical characterization methods to commercial manufacturing sites and work within teams to ensure successful regulatory submissions. - Conduct developability assessment to select molecules with higher probability of success for clinical development and eventual commercialization. - Profiling of physicochemical properties, development of preclinical formulations, identifying solutions to in vivo absorption challenges, and advancement of novel drug delivery strategies across multiple routes of administration that are aligned with program target product profiles and downstream partners. - Work in cross-functional teams in matrixed environments and engage in multidisciplinary problem solving. - Serve as a biopharm project leader within MPDD to support discovery and early clinical programs and lead peptide oral delivery programs. - Lead CMC developability assessment for emerging molecules on peptide and small molecule pipeline programs. - Contribute towards developing our drug delivery capabilities with a focus on complex chemically synthesized modalities. - Work collaboratively with discovery and development partners across disciplines to improve delivery of these modalities and advance molecules to clinical development with improved developability profiles. That's a lot; we can put as

    • items. Qualifications: education and experience. - Bachelors, Masters, or Ph.D. with 10+ (B.S.), 8+ (M.S.), and 1-3 (Ph.D.) years of experience in pharmaceutical or related industry. - Preferred educational backgrounds include but are not restricted to Pharmaceutical Sciences, Pharmaceutical Engineering, Chemical/ Biomedical Engineering, and Materials Science. - Fundamental understanding of biopharmaceutics as it relates to drug absorption across routes of administration including biorelevant dissolution testing, ex vivo permeability assessment, and peptide aggregation. - Familiarity and preferred hands-on experience in physicochemical property assessment related to understanding CMC developability profile and potential risk mitigation strategies. Techniques of interest include, but are not limited to: chromatography, DSF, rat intestinal perfusion, Ussing Chambers, Franz Diffusion cells, X-ray diffraction, thermal analysis, microscopy, biophysical characterization techniques, etc. - Experience developing and characterizing drug delivery systems to improve the bioperformance of peptides, in particular the use of permeation enhancer formulations. - Experience supporting GLP toxicology studies for oral peptide development. - Knowledge of preclinical and clinical formulation development principles relevant to chemically synthesized molecules across routes of administration. - Excellent self-management and organizational skills. - Demonstrated strong communication skills and ability to clearly communicate theories and concepts, influence others without authority, and drive technical excellence. We could separate qualifications (education/experience) and skills (soft skills). But we can combine under Qualifications heading and maybe Skills heading for soft skills. But we need to avoid thin sections. Perhaps we can have: - About the role (short paragraph summarizing role) - Responsibilities (ul) - Qualifications (ul) covering education/experience and technical knowledge - Skills (ul) covering communication, self-management, etc. - Benefits (ul) - Pay (p) We need to ensure we don't create sections with placeholder text. All have content. Now we need to remove boilerplate: EEO statements, accommodation links, etc. Also remove duplicated lines (the job description appears twice; we need to deduplicate). We'll keep unique content. Also remove "Company Description About AbbVie ..." maybe we keep as intro paragraph. Let's craft HTML. We'll start with a

      for company description: "AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube." Then maybe an

      About the role

      with a short paragraph summarizing: "The Senior Scientist I in the Molecular Profiling and Drug Delivery (MPDD) function will serve as a biopharm project leader, lead peptide oral delivery programs, and drive CMC developability assessment for emerging molecules on peptide and small molecule pipeline programs, working cross-functionally to improve drug delivery capabilities for complex chemically synthesized modalities." Then Responsibilities

      Responsibilities

      with
      • ... each duty. We need to ensure we don't duplicate similar items. Let's list responsibilities uniquely: 1. Utilize state-of-the-art automation and computational tools supported by expertise in biopharmaceutics, drug delivery, and solid-state chemistry to progress candidates with higher probability of success into development and advise clinical formulation strategy. 2. Identify the commercial solid form of the active pharmaceutical ingredient (API) and establish structure-property-performance correlations to deliver robust commercial processes and align control strategies across drug substance and product. 3. Transition drug substance isolation processes and relevant physical characterization methods to commercial manufacturing sites and work within teams to ensure successful regulatory submissions. 4. Conduct developability assessment to select molecules with higher probability of success for clinical development and eventual commercialization, including profiling of physicochemical properties, development of preclinical formulations, identifying solutions to in vivo absorption challenges, and advancement of novel drug delivery strategies across multiple routes of administration aligned with program target product profiles and downstream partners. 5. Work in cross-functional teams in matrixed environments and engage in multidisciplinary problem solving. 6. Serve as a biopharm project leader within MPDD to support discovery and early clinical programs and lead peptide oral delivery programs. 7. Lead CMC developability assessment for emerging molecules on peptide and small molecule pipeline programs. 8. Contribute towards developing drug delivery capabilities with a focus on complex chemically synthesized modalities. 9. Collaborate with discovery and development partners across disciplines to improve delivery of these modalities and advance molecules to clinical development with improved developability profiles. That covers. Now Qualifications

        Qualifications

        with education/experience and technical knowledge. Items: - Bachelors, Masters, or Ph.D. with 10+ (B.S.), 8+ (M.S.), and 1-3 (Ph.D.) years of experience in pharmaceutical or related industry. - Preferred educational backgrounds include Pharmaceutical Sciences, Pharmaceutical Engineering, Chemical/Biomedical Engineering, and Materials Science. - Fundamental understanding of biopharmaceutics as it relates to drug absorption across routes of administration including biorelevant dissolution testing, ex vivo permeability assessment, and peptide aggregation. - Familiarity and preferred hands-on experience in physicochemical property assessment related to understanding CMC developability profile and potential risk mitigation strategies (techniques: chromatography, DSF, rat intestinal perfusion, Ussing Chambers, Franz Diffusion cells, X-ray diffraction, thermal analysis, microscopy, biophysical characterization techniques, etc.). - Experience developing and characterizing drug delivery systems to improve the bioperformance of peptides, in particular the use of permeation enhancer formulations. - Experience supporting GLP toxicology studies for oral peptide development. - Knowledge of preclinical and clinical formulation development principles relevant to chemically synthesized molecules across routes of administration. Now Skills

        Skills

        with soft skills: - Excellent self-management and organizational skills. - Demonstrated strong communication skills and ability to clearly communicate theories and concepts, influence others without authority, and drive technical excellence. Now Benefits

        Benefits

        with ul: - Paid time off (vacation, holidays, sick) - Medical/dental/vision insurance - 401(k) eligibility - Eligibility to participate in short-term incentive programs Now Pay

        Pay

        with p: The compensation

Similar jobs