Sr. Science & Health Advisor, Guidelines, AHA/ACC

Responsibilities

• Lead and evolve guideline methodology
• Oversee the development, application, and continuous improvement of American Heart Association/ACC guideline methodology, ensuring consistency, rigor, and alignment across all guideline product
• Maintain and update the American Heart Association/ACC Guideline Methodology and Policies Manual to reflect current standards and best practices
• Champion AI-enabled guideline development
• Lead the AI-LLM–first strategy for guideline development, including design, development, and deployment of AI agents/workflows for evidence review, data extraction, and content drafting; oversee prompt engineering, validation, and continuous optimization
• Partner with the American Heart Association/ACC National Senior Director to scale AI-enabled methodologies across guideline advisors and volunteer committees
• Provide methodological oversight across guideline development
• Conduct a comprehensive methodological review of recommendations, evidence grading (COR/LOE), and associated figures throughout key development milestones, including peer review
• Ensure consistent and appropriate application of methodological standards, including evidence classification, FDA considerations, and cost-effectiveness analyses
• Ensure consistent, error-free application of methodological standards across all guideline documents, minimizing variability and post-review corrections
• Lead guideline projects and pragmatic updates
• Serve as a primary liaison and project lead for guidelines undergoing pragmatic updates, ensuring alignment with methodological standards, timelines, and Joint Committee expectations
• Cook up relationships with industry (RWI) implementation and compliance
• Supervise the Compliance Operations Manager for RWI processes, ensuring highly accurate, error-free documentation, timely disclosures, and adherence to the American Heart Association/ACC RWI procedure.
• Monitor and ensure full compliance with the joint documents, committees, and contributors.
• Oversee documentation and processes that ensure audit readiness and consistency across the full guideline portfolio
• Develop and train guideline contributors
• Design and deliver training programs (synchronous and asynchronous) for writing committee members and reviewers on guideline methodology and evidence evaluation frameworks
• Promote adoption of best practices in evidence review and recommendation development
• Supervise and develop staff
• Manage and mentor direct reports, ensuring effective project execution, professional development, and alignment with organizational priorities
• Support staff in navigating complex volunteer and guideline development environments
• Contribute to team and organizational priorities
• Support cross-functional initiatives and evolving priorities related to guideline methodology and innovation

Qualifications

• Bachelor’s degree in Public Health, Epidemiology, or a related health, life science, or medical research discipline
• 5+ years of relevant experience
• 5+ years of experience in medical writing, scientific editing, guideline development, or clinical research
• 2–5 years of experience supporting or overseeing clinical guideline development and/or methodology application
• 2–5 years of experience managing direct reports or leading staff/project teams
• Demonstrated expertise and success in comprehensive evidence review, evidence synthesis, and development of evidence tables
• Strong understanding of clinical research methods, evidence grading frameworks (e.g., COR/LOE), and guideline development processes
• Proven ability and success in managing multiple complex projects simultaneously in a deadline-driven environment
• Excellent written and verbal communication skills, including advanced editing and proofreading proficiency
• Strong interpersonal and leadership skills, with experience working with cross-functional teams, volunteer experts, and senior stakeholders
• Proficiency with Microsoft Office, reference management tools (e.g., EndNote), Adobe Acrobat, and workflow/content management platforms
• Ability to travel approximately 5-10%, including occasional overnight travel

Preferred Qualifications

• Advanced degree (e.g., MPH, MS, PhD) in Public Health, Epidemiology, or a related field
• Extensive experience contributing to clinical practice guidelines, scientific statements, or other evidence-based publications
• Experience developing or applying guideline methodology frameworks at scale
• Experience leading or implementing AI-enabled or technology-driven approaches to evidence review or content development
• Familiarity with workflow/project management tools and structured content management systems