Sr. Research Scientist, Myeloid Diseases – Incyte
Delaware Thrive · Wilmington, DE · 2 wk ago
Full-time
Location: Wilmington, Delaware
About the role
We are seeking a Senior Research Scientist to join our Myeloid Diseases team. This role will focus on advancing our understanding and development of therapies for myeloid malignancies.
Responsibilities
- Design, execute, and interpret experiments to identify and validate novel drug targets in myeloid diseases.
- Develop and implement in vitro and in vivo models to evaluate therapeutic candidates.
- Collaborate with cross-functional teams, including biology, pharmacology, and translational research, to advance drug discovery programs.
- Analyze and present data to internal and external stakeholders, contributing to scientific publications and presentations.
- Stay current with scientific literature and emerging technologies in the field of myeloid diseases.
- Mentor junior scientists and contribute to a culture of scientific excellence and innovation.
Requirements
- Ph.D. in Biology, Molecular Biology, Biochemistry, or a related field with a minimum of 5 years of postdoctoral or industry experience in myeloid disease research.
- Strong expertise in hematopoiesis, leukemia biology, or related areas, with a track record of publications in peer-reviewed journals.
- Hands-on experience with techniques such as flow cytometry, cell culture, CRISPR/Cas9 gene editing, and molecular biology assays.
- Proficiency in in vivo models of hematologic malignancies, including xenograft and syngeneic models.
- Experience with drug discovery and development processes, including target identification, validation, and lead optimization.
- Excellent problem-solving skills and the ability to work independently as well as in a team environment.
- Strong communication skills, with the ability to present complex data clearly and concisely.
Skills
- Flow cytometry and cell sorting (e.g., FACS)
- CRISPR/Cas9 gene editing and functional genomics
- In vivo modeling (xenograft, syngeneic, PDX models)
- Molecular and cellular biology techniques (qPCR, Western blot, ELISA, etc.)
- Data analysis and visualization (e.g., GraphPad Prism, R, Python)
- Scientific writing and presentation