Sr. Director of Enterprise Program Management Office

About the role

The Sr. Director of Enterprise Program Management Office (ePMO) plays a highly collaborative and internally focused leadership role responsible for driving alignment, coordination, and execution across the organization. This position serves as a central connector across functions including Operations, Quality, Supply Chain, Manufacturing, Technical Operations, Engineering, R&D, Commercial, and Corporate functions to ensure enterprise priorities are effectively integrated and executed.

Responsibilities

• Lead and coordinate enterprise-wide programs, projects, and strategic initiatives that require collaboration across multiple departments and functions.
• Develop and maintain consistent project management methodologies, tools, templates, and systems that support organizational alignment, operational agility, and business process standardization.
• Partner closely with leaders and teams across the organization to ensure initiatives remain aligned with company strategy, operational priorities, resource capacity, compliance requirements, and business objectives.
• Serve as a key internal partner and facilitator, helping teams navigate cross-functional dependencies, resolve barriers, improve communication, and maintain execution momentum.
• Build and strengthen the ePMO as a collaborative internal function and Community of Practice that supports organizational effectiveness, continuous improvement, and a culture of accountability and execution excellence.
• Support organizational decision-making by providing executive leadership with clear program visibility, dashboards, reporting, risk assessments, and progress updates.
• Provide guidance, coaching, and mentorship to project managers and cross-functional teams to strengthen project management capabilities across the organization.
• Act as a trusted internal consultant and advisor to project sponsors, department leaders, and governance committees on project execution, prioritization, and organizational coordination.
• Collaborate with executive leadership on strategic planning, enterprise prioritization, and organizational initiatives that support business growth and operational maturity.
• Oversee operational and budgetary management of the ePMO function.

Requirements

• 10+ years of experience in project management, program management, operations, technical operations, manufacturing, or related leadership roles within pharmaceutical, biotechnology, CDMO, or small molecule manufacturing environments.
• Broad cross-functional experience across multiple areas of a small molecule pharmaceutical manufacturing organization strongly preferred.
• Demonstrated ability to work effectively across departments and influence without direct authority in a highly collaborative environment.
• Strong understanding of pharmaceutical manufacturing operations, organizational interdependencies, and regulated environments.
• Proven ability to manage complex enterprise initiatives involving multiple stakeholders, priorities, and timelines.
• Excellent communication, facilitation, organizational, and relationship-building skills.

Qualifications

• Bachelor’s degree in a related field required.
• PMP certification preferred.

Physical Requirements

• Constantly required to see to utilize computer screens and monitors to perform job duties including reading & writing, as well as when presenting information and communicating with others.
• Frequently required to talk or hear to communicate with employees, candidates, vendors, and others, including presenting information in front of groups.
• Frequently required to sit, and occasionally required to stand or walk to move around primarily in an office environment.