Sr Associate Scientist, Product Biochemistry

About the role

Regeneron is seeking a Sr Associate Scientist to join the Product Biochemistry team on‑site in Tarrytown, NY. The role supports late‑stage development (Phase II through commercialization) of biologics by developing and deploying analytical methods, purification strategies, and characterizing product variants. The position offers the chance to apply scientific creativity, efficiency, and flexibility in a fast‑paced, science‑driven organization.

Responsibilities

• Develop analytical methods and purification protocols for extended characterization of therapeutic proteins and gene‑therapy vectors.
• Conduct biochemical/biophysical characterization to support development, regulatory submissions, and commercialization.
• Apply design of experiments (DOE), advanced statistics, and risk assessments to evaluate and optimize methods and processes.
• Design and execute experiments to enrich, purify, and characterize size/charge variants, complexes, and high‑concentration formulations.
• Independently operate U/HPLCs and AKTA FPLCs, and perform capillary‑based electrophoresis.
• Integrate internal data and external literature to make science‑based study design recommendations.
• Author high‑quality technical documents (protocols, reports, memos), contribute to regulatory sections and publications, and ensure timely documentation in accordance with SOPs and guidelines.
• Document experiments, results, and findings in the electronic laboratory notebook and present work at group and department meetings.
• Maintain instruments, troubleshoot instrumental/experimental problems, order and maintain supplies, and improve lab/data workflows within the area of expertise.

Requirements

• BS/MS in Biochemistry, Biophysics, Engineering, or a related field.
• 4–6+ years of relevant industry experience.
• Strong lab skills in protein separation, purification, and tangential flow filtration (TFF).
• Experience with protein/product identification using mass spectrometry.
• Excellent oral and written communication skills and demonstrated teamwork.
• Strong initiative, ability to learn new technologies, and commitment to continuous learning.
• Ability to communicate clearly, transparently, and in a timely manner with key stakeholders.

Preferred qualifications

• Technical proficiency in automated FPLC and/or HPLC (SEC, IEX, affinity), electrophoresis (capillary or microchip, SDS‑PAGE, western blots), spectroscopy, and light scattering.
• Fundamental understanding of protein structure/function, mass spectrometry, and immunology/immunogenicity.
• Experience working in the biopharmaceutical industry.

Benefits

• Student Loan Paydown program & Tuition Reimbursement
• Family Care Benefits
• Relocation Assistance
• Inclusion, Culture and Well‑Being programs (including physical & mental health)
• Competitive total rewards package that may include annual bonuses, equity awards, pension/retirement benefits, 401(k) match, health and wellness programs, fitness centers, insurance (medical, dental, vision, life, disability), paid time off, and family support benefits.

Pay

Salary range (annually): $80,300.00 – $131,100.00

Schedule

Full‑time, standard business hours. Minimal to no travel; on‑site presence required to support laboratory operations.