Senior Technical Operations Manager

About the role

The Senior Technical Operations Manager at Rapport is responsible for driving cross-functional execution across CMC, Supply Chain, Quality, and Toxicology to advance small molecule programs from early development through late-stage clinical development and NDA submission. This role combines program management with operational logistics, ensuring alignment of timelines, deliverables, and resources across internal teams and external partners.

Responsibilities

• Coordinate cross-functional program execution across CMC, Quality, Supply Chain, and Toxicology
• Maintain integrated development plans, timelines, and program documentation
• Track key milestones, risks, action items, and support program communications
• Care for logistics for raw materials, API, drug product, and clinical/nonclinical supplies, including inventory, shipments, and documentation
• Ensure operational readiness to support regulatory milestones and development activities
• Coordinate CDMO and CRO activities to support program timelines and deliverables
• Support SOW execution, vendor performance tracking, and budget management
• Collaborate with Finance and functional teams to monitor program expenditures
• Work independently in a fast-paced, dynamic environment while maintaining a high level of accuracy and accountability

Requirements

• Bachelor's degree in a life sciences, engineering, supply chain, or related field
• 5+ years of experience in CMC operations, supply chain, logistics, or project management within the biotechnology or pharmaceutical industry
• Demonstrated experience managing complex logistics, including material planning, inventory, vendor coordination, and time-sensitive shipments
• Highly organized with exceptional attention to detail and the ability to manage multiple priorities across cross-functional teams
• Experience working with CDMOs, CROs, and external vendors in a regulated GMP/GxP environment
• Strong project management and communication skills with a proven ability to track timelines, risks, budgets, and deliverables
• Proficiency with Microsoft Office (Excel, PowerPoint, Project) and document management/project tracking systems

Qualifications

• Ability to work independently in a fast-paced, dynamic environment while maintaining a high level of accuracy and accountability

Skills

• Strong CMC program management expertise
• Operational rigor
• Proactive risk identification and mitigation

Benefits

• Competitive benefits including unlimited PTO, a lifestyle spending account, commuting reimbursement, and much more!

Pay

Our actual offer will reflect a lot of factors including your relevant skills, experience, location, salary market data, and internal equity. In addition to a competitive salary, we also offer a pretty great benefits package.

Schedule

This role is based in Boston, MA with onsite presence required Monday-Wednesday.