Senior Systems Engineer, IVD Software

About the role

The Sr. Systems Engineer at Veracyte is responsible for the system architecture, reliability, and long-term operability of a commercial in vitro diagnostic (IVD) software product deployed across diverse customer environments. This role focuses on customer-facing product systems and requires deep expertise in Windows-based platforms, distributed systems, and hybrid infrastructure.

Responsibilities

• Own and evolve the system-level architecture of a Windows-based IVD software product deployed to customer environments.
• Act as a system-level technical authority, influencing architecture and design decisions without formal people management.
• Design, configure, and support product deployments using IIS, SQL Server, WSL, and Docker across on-premises, virtualized, and cloud environments.
• Anticipate, identify, and mitigate environment-specific risks across Windows and Linux systems, virtual machines, containers, networking, and cloud infrastructure.
• Support and stabilize a distributed product maintained over multiple years across a large enterprise install base (100+ customer installations).
• Lead deep root-cause analysis of complex issues spanning application behavior, operating systems, databases, containers, and infrastructure.
• Define, document, and enforce supported deployment models, environment assumptions, constraints, and known failure modes.
• Partner early with software engineering to surface non-obvious system dependencies, scalability limits, and operational risks.
• Influence CI/CD pipelines and release processes to improve reliability, repeatability, and diagnosability in regulated environments.
• Apply security best practices to product systems, including hardening, access control, patching strategies, and vulnerability management.
• Drive improvements in observability through logging, monitoring, diagnostics, and operational tooling.
• Develop and maintain automation scripts to reduce manual configuration, increase consistency, and eliminate classes of environment-related issues.
• Ensure system designs, configurations, and documentation meet IVD regulatory and quality expectations.
• Create and maintain system architecture documentation, deployment guides, and operational playbooks.
• Serve as a senior escalation point and mentor for system-level issues, raising the bar for system engineering practices.

Requirements

• Bachelor’s degree in Computer Science, Engineering, or a related field, or equivalent practical experience.
• A minimum of 6 – 7 years of experience supporting commercial product software.
• Deep hands-on experience with Windows Server environments, including IIS and SQL Server in production.
• Strong working knowledge of Linux systems (e.g., Ubuntu, RHEL-based distributions) in product deployments.
• Proven experience with Docker and containerized application deployments.
• Hands-on experience with AWS services such as EC2, VPC, IAM, and storage services.
• Demonstrated ability to proactively diagnose and resolve complex system-level issues across software, OS, and infrastructure layers.
• Experience developing automation scripts using Bash, PowerShell, Python, or similar languages.
• Familiarity with CI/CD pipelines and release workflows in regulated or quality-focused environments.
• Strong troubleshooting, problem-solving, and communication skills.

Preferred Qualifications

• Direct experience supporting IVD, medical device, or other regulated software products.
• Experience maintaining a distributed product for 2–3 years across 100+ enterprise customer installations.
• Exposure to container orchestration platforms such as ECS, EKS, or Kubernetes.
• Experience with infrastructure as code or configuration management tools.
• Familiarity with monitoring and logging platforms and operational diagnostics.
• Background in regulated environments with awareness of compliance and audit expectations.
• Demonstrated ability to influence system architecture and technical direction at a product level without formal management responsibility.

Pay

The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to years of experience, skillset, geographic location, industry, education, etc. Base pay is one part of the Total Package that is provided to compensate and recognize employees for their work, and this role may be eligible for additional discretionary bonuses/incentives, and restricted stock units. Pay range $183,000—$225,000 USD